ReviewClinical, cosmetic and investigational dermatology2026
Challenges in the Diagnosis and Management of Nail Melanocytic Disorders.
Review in Clinical, cosmetic and investigational dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melanonychia significantly affects aesthetics and patient well-being, particularly when it advances to subungual melanoma. The causes of melanonychia are multifactorial, encompassing nail matrix melanocyte activation, benign melanocytic proliferation, subungual melanoma, as well as inflammatory, infectious, traumatic, and drug-induced conditions. Among these, subungual melanoma poses a diagnostic challenge due to its nonspecific clinical presentation, leading to delayed or missed diagnoses that adversely affect prognosis. Accurate differentiation between malignant melanonychia and more common benign etiologies-such as onychomycosis, trauma-related pigmentation, drug-induced pigmentation, and subungual warts-is essential to avoid both misdiagnosis and overtreatment. This review summarizes the clinical, dermoscopic, and histopathological characteristics of melanonychia of various origins; highlights key dermoscopic features for distinguishing subungual melanoma from non-melanocytic pigmentation; and outlines diagnostic and therapeutic strategies tailored to both adults and children. Clarifying these distinctions is critical for facilitating earlier recognition of nail melanoma while minimizing unnecessary interventions for benign conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.