SynthesisFrontiers in nutrition2026
Impact of frailty on outcomes of pancreatic surgery: a systematic review and meta-analysis.
Synthesis in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Objective: Frailty is being recognized as a risk factor for adverse outcomes after various surgical procedures. However, its impact on pancreatic surgery outcomes remains uncertain. We hereby reviewed evidence on the difference in the risk of complications and mortality between frail and non-frail patients undergoing pancreatic surgery. Methods: PubMed, Embase, Scopus, and Web of Science were searched from 1 Results: A total of 11 studies were included. A pooled analysis revealed that frailty was associated with an increased risk of all complications in patients undergoing pancreatic surgery (OR: 1.51, 95% CI: 1.01-2.24, I Conclusion: The presence of preoperative frailty may lead to increased risk of short-term mortality and morbidity in patients undergoing pancreatic surgery. Frailty was not associated with major complications, readmission, or reoperations. However, results must be interpreted with caution owing to limited data and high inter-study heterogeneity. Systematic review registration: https://www.crd.york.ac.uk/prospero/, CRD420251049842.
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