ArticleFrontiers in microbiology2026
Development and optimization of an easy to interpret loop-mediated isothermal amplification (LAMP) assay for the identification of bacterial pathogens causing childhood pneumonia.
Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Pneumonia remains the leading infectious cause of death in children under five, especially in low-resource settings. Reducing mortality requires rapid, accessible, and reliable diagnostic tools. In this regard, the loop-mediated isothermal amplification (LAMP) technique has emerged as a fast and efficient alternative for simple pathogen detection. This study aimed to standardise and optimize a LAMP assay for detecting the main bacteria causing pneumonia in children, including Methods: Several fluorescent and colorimetric dyes were evaluated to identify those providing a clear readout visible to the naked eye. Once achieved, detection conditions for each pathogen in the panel were optimized, and the feasibility of the assay was assessed using respiratory clinical samples, including both confirmed positives and negatives for the bacteria targeted in the panel. Results and discussion: SYBR Safe, Calcein-Mn
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.