Evidence map›Paper›PMID 41847137›Full record

ArticleFrontiers in pharmacology2026

Antifungal and anti-virulence activities of cinnamon, thyme, and clove essential oils against

Islam Ahaik, Juan Carlos Nunez-Rodriguez, Sònia Abelló-Cros, Oscar Yanes, Samira Bouhdid, Toni Gabaldón

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Frontiers in fungal biology · 2026
    Article
  2. Frontiers in pharmacology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Islam AhaikBiotechnology and Applied Microbiology Team, Research Laboratory of Applied Chemistry and Microbiology and Biotechnology, Department of Biology, Faculty of Sciences, Abdelmalek Essaadi University, Tetouan, Morocco.
Juan Carlos Nunez-RodriguezInstitute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Sònia Abelló-CrosScientific and Technical Service, Rovira i Virgili University (URV), Tarragona, Spain.
Oscar YanesDepartment of Electronic Engineering, Institut d'Investigació Sanitària Pere Virgili (IISPV), Rovira i Virgili University (URV), Tarragona, Spain.
Samira BouhdidBiotechnology and Applied Microbiology Team, Research Laboratory of Applied Chemistry and Microbiology and Biotechnology, Department of Biology, Faculty of Sciences, Abdelmalek Essaadi University, Tetouan, Morocco.
Toni GabaldónInstitute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: The chemical composition of cinnamon, thyme and clove EOs was analyzed by gas chromatography-mass spectrometry (GC-MS). Antifungal activity was evaluated against eighteen Results: GC-MS identified cinnamaldehyde, thymol and eugenol as the dominant components of cinnamon, thyme and clove EOs, respectively (> 70% relative abundance). All EOs displayed antifungal activity, with cinnamon and thyme being the most potent. Both oils showed increased activity against multidrug-resistant strains of Conclusion: These results highlight the strong dual activity of EOs, supporting further exploration of their potential as complementary therapeutic options against

Indexed as

antifungal resistanceCandidaessential oilsnon-albicans Candidavirulence factors

Identifiers

PMID41847137
PMCPMC12989488

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.