Evidence map›Paper›PMID 41847110›Full record

ArticleiScience2026

SKA2 promotes gastric cancer progression by regulating glutathione metabolism.

Peng Zhang, Jianfeng Zhong, Ting Zhou, Depei Jiang, Zijing Wang, Meifang Ye, Lekun Fang, Huizhen Xiong, Honglei Chen

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Peng ZhangGuangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Disease, Guangdong Research Institute of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510065, China.
Jianfeng ZhongGastrointestinal Endoscopy Center, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen 518033, China.
Ting ZhouGastrointestinal Endoscopy Center, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen 518033, China.
Depei JiangGastrointestinal Endoscopy Center, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen 518033, China.
Zijing WangGastrointestinal Endoscopy Center, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen 518033, China.
Meifang YeGastrointestinal Endoscopy Center, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen 518033, China.
Lekun FangGuangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Disease, Guangdong Research Institute of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510065, China.
Huizhen XiongGastrointestinal Endoscopy Center, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen 518033, China.
Honglei ChenGastrointestinal Endoscopy Center, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen 518033, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of spindle and kinetochore-associated complex subunit 2 (SKA2) in gastric cancer (GC) pathogenesis remains largely undefined. Here, we report that SKA2 is overexpressed in GC and correlates with poor prognosis. Functionally, SKA2 silencing inhibits tumor growth, induces G2/M arrest, and promotes apoptosis both

Indexed as

BiochemistryCancerCell biology

Identifiers

PMID41847110
PMCPMC12990383

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.