ReviewPeerJ2026
Gut microbiota dysbiosis and the gut-lung axis: links to asthma and its common comorbidities.
Review in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Unknotting the nexus of asthma and neuroinflammation: from brain network alterations to therapeutic implications.Journal of neuroinflammation · 2026Review
- The Gut-Lung Microbiome Crosstalk and Pulmonary Disease.Biomolecules · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma is a heterogeneous chronic inflammatory airway disease that frequently coexists with multiple comorbidities, including obesity, allergic rhinitis, chronic rhinosinusitis, and gastroesophageal reflux disease (GERD). These conditions substantially increase disease burden and complicate asthma management. Increasing evidence suggests that gut microbiota dysbiosis represents a shared biological factor linking asthma and its comorbidities through immune and metabolic pathways operating along the gut-lung axis. This narrative review summarizes current knowledge on how alterations in gut microbial composition and function influence immune homeostasis, chronic inflammation, and disease susceptibility in asthma and its common comorbid conditions. Particular emphasis is placed on microbial metabolites such as short-chain fatty acids, early-life immune programming, bidirectional gut-lung immune communication, and emerging microbiota-targeted interventions. Understanding the systemic role of the gut microbiota may provide novel insights into integrated prevention and management strategies for asthma and its comorbidities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.