Evidence map›Paper›PMID 41847024›Full record

ArticlebioRxiv : the preprint server for biology2026

Photomapping electrically coupled networks of the mature thalamus and cortex.

Mitchell J Vaughn, David S Uygun, Radhika Basheer, Kevin J Bender, Julie S Haas

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mitchell J VaughnDepartment of Biological Sciences, Lehigh University, 111 Research Drive, Bethlehem, PA 18015 USA.ORCID 0000-0003-4117-7120
David S UygunVA Boston Healthcare System and Harvard Medical School, Dept. of Psychiatry, West Roxbury, MA 02132, USA.ORCID 0000-0003-3143-9975
Radhika BasheerVA Boston Healthcare System and Harvard Medical School, Dept. of Psychiatry, West Roxbury, MA 02132, USA.ORCID 0000-0002-4052-6897
Kevin J BenderWeill Institute for Neurosciences and Department of Neurology, University of California, San Francisco; San Francisco, CA, USA.ORCID 0000-0001-7084-1532
Julie S HaasDepartment of Biological Sciences, Lehigh University, 111 Research Drive, Bethlehem, PA 18015 USA.ORCID 0000-0002-1571-8512

Funding

Identifying Electrically Coupled Networks in vitroR01NS128713 · NINDS · LEHIGH UNIVERSITY · PI JULIE S HAAS · 2022 to 2026
$1.9M
Neural Correlates of Sleep HomeostasisR01NS119227 · NINDS · HARVARD MEDICAL SCHOOL · PI BASHEER, RADHIKA · 2021 to 2025
$1.6M
BLRD VA I01 BX006105BLRD VA IK2 BX004905NINDS NIH HHS R01 NS119227NINDS NIH HHS R01 NS128713
6 · The paper itself

Abstract

Electrical synapses are expressed ubiquitously across the brain and are crucial components of active neural circuitry and connectomes. Identification of coupled networks in living tissue is limited by technical demands of multiplexed recordings, and no dyes, fluorescent reporters, or genetic labels can currently fill the gap. We introduce a novel method of identifying and quantifying electrical synapses, opto-δL, that combines focal photostimulation of soma-targeted opsins with a spike timing-based computation for the strength of electrical synapses to rapidly measure and map electrically coupled networks

Identifiers

PMID41847024
PMCPMC12991111

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.