Evidence map›Paper›PMID 41846975›Full record

ArticlebioRxiv : the preprint server for biology2025

Colibactin produced by a honeybee symbiont defends against pathogens and shapes the gut community.

Yulin Song, J Elijah Powell, Joel W H Wong, Yunxi Liu, Miguel A Aguilar Ramos, Tyler De Jong, Patrick J Lariviere, Jayaditya Maganti, Emily P Balskus, Nancy A Moran

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Yulin SongDepartment of Integrative Biology, University of Texas, Austin, TX 78712, USA.ORCID 0000-0002-9318-8158
J Elijah PowellDepartment of Integrative Biology, University of Texas, Austin, TX 78712, USA.ORCID 0000-0002-2758-6174
Joel W H WongDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0003-4627-4878
Yunxi LiuDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0002-5253-582X
Miguel A Aguilar RamosDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0002-2537-8371
Tyler De JongDepartment of Integrative Biology, University of Texas, Austin, TX 78712, USA.ORCID 0009-0005-9937-6415
Patrick J LariviereDepartment of Integrative Biology, University of Texas, Austin, TX 78712, USA.ORCID 0000-0002-8427-3879
Jayaditya MagantiDepartment of Integrative Biology, University of Texas, Austin, TX 78712, USA.
Emily P BalskusDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0001-5985-5714
Nancy A MoranDepartment of Integrative Biology, University of Texas, Austin, TX 78712, USA.ORCID 0000-0003-2983-9769

Funding

Elucidating the molecular bases of species interactions in host-associated bacterial communitiesR35GM131738 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI MORAN, NANCY A. · 2019 to 2023
$2.0M
The molecular bases of interbacterial and bacterial-host interactions in microbial communitiesR35GM158145 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Nancy A. Moran · 2025 to 2026
$793k
NIGMS NIH HHS R35 GM131738NIGMS NIH HHS R35 GM158145
6 · The paper itself

Abstract

Colibactin is a bacterial genotoxin that is linked to colorectal cancer and implicated in interbacterial competition; however, its role in natural communities remains unknown.

Indexed as

ColibactinDNA damagegut microbiotahoneybeeinterbacterial competition

Identifiers

PMID41846975
PMCPMC12990990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.