Evidence map›Paper›PMID 41846906›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2026

A Novel Nomogram for Diabetic Retinopathy Prediction in Young and Middle-Aged Patients with Type 2 Diabetes.

Leilei Ma, Surui Shi, Jingfei Wang, Shousen Shi, Yingfeng Zhang, Xi Wang, Shuaibo Shi, Ke Huang, Yanfang Zhang

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Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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9 authors.

Leilei MaDepartment of Graduate, Henan Medical University, Xinxiang, Henan, People's Republic of China.
Surui ShiDepartment of Graduate, Henan Medical University, Xinxiang, Henan, People's Republic of China.
Jingfei WangDepartment of Endocrinology, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan, People's Republic of China.
Shousen ShiDepartment of Gastrointestinal Surgery, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan, People's Republic of China.
Yingfeng ZhangDepartment of Endocrinology, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan, People's Republic of China.
Xi WangDepartment of Endocrinology, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan, People's Republic of China.
Shuaibo ShiDepartment of Graduate, Henan Medical University, Xinxiang, Henan, People's Republic of China.
Ke HuangDepartment of Endocrinology, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan, People's Republic of China.
Yanfang ZhangDepartment of Endocrinology, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The study aims to develop and validate a novel nomogram for predicting diabetic retinopathy (DR) risk specifically in young and middle-aged patients with type 2 diabetes (T2DM). Methods: This retrospective cohort study analyzed 337 T2DM patients (Age 15-59 years) admitted to Luoyang Central Hospital from July 2022 to January 2024, stratified by fundus examination into DR (n=155) and non-DR (n=182) groups. Demographic characteristics and relevant clinical parameters were systematically collected. A predictive nomogram for DR detection was constructed using significant variables identified through multivariate logistic regression analysis. The calibration, discrimination, and clinical utility of the nomogram were subsequently evaluated using calibration plots, receiver operating characteristic curves, and decision curves. Results: Multivariate analysis identified four independent predictors of diabetic retinopathy: diabetes duration (OR=1.125, 95% CI: 1.07-1.182, Conclusion: This study presents the first nomogram for DR risk in young and middle-aged patients with T2DM. Integrating four routine clinical parameters (diabetes duration, baPWV, BUN, age), the model demonstrates robust predictive power (AUC=0.75) and clinical utility, enabling early risk stratification and timely intervention.

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brachial-ankle pulse wave velocitydiabetic retinopathyline graphsprediction models

Identifiers

PMID41846906
PMCPMC12991373

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.