ArticleJournal of pharmacy & bioallied sciences2025
Effectiveness of Different Agents in Ceasing Early Childhood Caries: A Clinical Study.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Early childhood caries (ECC) remains a prevalent global health issue, particularly in developing nations. Effective interventions are critical to halting its progression and preventing long-term dental complications. This study aimed to evaluate the effectiveness of different caries-arresting agents in ceasing ECC. Methods: A randomized clinical trial was conducted on 150 children aged 2-5 years with ECC. Participants were divided into three groups and treated with silver diamine fluoride (SDF), fluoride varnish (FV), or glass ionomer cement (GIC). Caries progression was evaluated at baseline, 3 months, and 6 months using standardized indices. Results: SDF showed the highest efficacy in arresting caries lesions, with 85% of lesions arrested by 6 months. FV and GIC exhibited 70% and 60% effectiveness, respectively. Both SDF and FV demonstrated significant reductions in caries progression compared with GIC ( Conclusion: SDF is the most effective agent in ceasing ECC progression, followed by FV and GIC. Routine use of SDF could significantly impact pediatric dental health.
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