Evidence map›Paper›PMID 41846694›Full record

ArticleERJ open research2026

"Breathlessness stops me doing everything": exploring the impact of chronic breathlessness due to advanced respiratory disease and exacerbating factors - a qualitative study.

Charles C Reilly, Irene J Higginson, Anna Roach, Trudie Chalder, Katherine Bristowe

Abstract read
In one paragraph

Article in ERJ open research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Charles C ReillyDepartment of Physiotherapy, King's College Hospital, London, UK.ORCID https://orcid.org/0000-0003-2520-2859
Irene J HigginsonCicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King's College London, London, UK.ORCID https://orcid.org/0000-0002-3687-1313
Anna RoachCicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King's College London, London, UK.
Trudie ChalderKing's College London, Institute of Psychiatry, Department of Psychological Medicine, London, UK.
Katherine BristoweCicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King's College London, London, UK.ORCID https://orcid.org/0000-0003-1809-217X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Breathlessness is a global, transdiagnostic problem, contributing to disability, reduced quality of life and higher healthcare costs. As the global population ages and multimorbidity increases, the prevalence of breathlessness is expected to rise. Therefore, there is an urgent need to co-design new services and treatments for breathlessness. To achieve this, it is essential to understand the lived experience of breathlessness. This study aimed to explore the lived experience of chronic breathlessness, focusing on its impact and contributing factors that exacerbate breathlessness. Methods: Semi-structured telephone interviews were conducted with adults experiencing chronic breathlessness caused by advanced malignant and nonmalignant diseases (July to November 2020). The interviews were analysed using conventional content analysis. Results: 25 patients with advanced respiratory disease and chronic breathlessness ((COPD, 13; lung cancer, 8; interstitial lung disease, 3; and bronchiectasis, 1), 17 male, median age 70 years (range 47-86), Medical Research Council dyspnoea score 3 (2 -5)) were interviewed. Four key themes were identified: 1) the impact of breathlessness on daily activities, leading to increased dependence on others; 2) the effect of breathlessness on social interactions and personal relationships, resulting in isolation; 3) the impact of living with multiple long-term conditions and environmental factors that worsen breathlessness; and 4) cognitive, affective and behavioural responses to breathlessness. Conclusion: Breathlessness significantly disrupts daily life, limiting independence and social engagement, with psychological and behavioural responses further restricting activity. An integrated, public health approach, collaborating with housing and environmental agencies is essential to address modifiable factors and reduce the burden on individuals and healthcare systems.

Identifiers

PMID41846694
PMCPMC12991001

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.