Evidence map›Paper›PMID 41846637›Full record

ArticleCureus2026

A Case of Amyloid Light-Chain Amyloidosis Presenting as Colitis.

Karpagapriya Prabakaran, Sarosh Khan, Ling Mei, Francis Edeani, Patrick Sanvanson, Priyadharshini Sivasubramaniam, Mahmoud Ali, Gokulakrishnan Balasubramanian

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karpagapriya PrabakaranDivision of Gastroenterology and Hepatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, USA.
Sarosh KhanDivision of Gastroenterology and Hepatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, USA.
Ling MeiDivision of Gastroenterology and Hepatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, USA.
Francis EdeaniDivision of Gastroenterology and Hepatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, USA.
Patrick SanvansonDivision of Gastroenterology and Hepatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, USA.
Priyadharshini SivasubramaniamDepartment of Pathology, Medical College of Wisconsin, Milwaukee, USA.
Mahmoud AliDepartment of Pathology, Medical College of Wisconsin, Milwaukee, USA.
Gokulakrishnan BalasubramanianDivision of Gastroenterology and Hepatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal amyloidosis is a rare but often a manifestation of an advanced form of systemic amyloidosis that carries a poor prognosis. Its presentation may mimic ischemic bowel disease, inflammatory bowel disease, celiac disease, or protein-losing enteropathy, among others. Often, varied presentations make it difficult to diagnose. Hence, a careful and systematic approach with an aggressive treatment strategy is needed for prompt diagnosis and treatment of the fatal condition. Here, we report a fatal case of systemic amyloidosis (amyloid light-chain (AL) amyloidosis) with its initial presentation including gastrointestinal symptoms and subsequent rapid clinical deterioration due to worsening renal function and evidence of pericardial effusion.

Indexed as

amyloidosiscolitiscolonic amyloidosisgastrointestinal amyloidosislower gastrointestinal bleeding

Identifiers

PMID41846637
PMCPMC12991382

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.