ArticleFrontiers in plant science2026
Crosstalk between glutathione and melatonin in chromium detoxification in sweet potato revealed by high-throughput sequencing and physio-biochemical profiling.
Article in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Chromium (Cr) contamination severely inhibits plant productivity, primarily by disrupting photosynthetic performance, growth, and inducing oxidative stress. This study investigated the comparative molecular mechanisms by which exogenous glutathione (GSH) and melatonin (MT) confer tolerance to Cr stress in sweet potato using an integrated transcriptomic approach. Transcriptome analysis identified 7,734 differentially expressed genes (DEGs) across Cr stress and mitigator treatments. The GO and KEGG pathway enrichment analyses showed that DEGs were mainly enriched in GO terms, such as photosynthesis, carbon fixation, and cell-wall organization, as well as pathways including MAPK signaling, glutathione metabolism, plant hormone signal transduction, and membrane/vesicle transport. These DEGs were subjected to cluster analysis, and four major expression clusters (C1-C4) were identified, with DEGs ranging from 1,234 to 3,285. GSH-specific protection was associated with Cluster C4, enhancing genes involved in ROS defense, H
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