Evidence map›Paper›PMID 41846544›Full record

ArticleThe British journal of surgery2026

Epidemiology of trauma deaths across a mature regional trauma system: patterns of prehospital and in-hospital fatalities.

Aditi Nijhawan, Ewoud Ter Avest, Callum J Twohig, Stacey J Webster, Jared M Wohlgemut, Jason Morris, Robbie Lendrum, Virginia Fitzpatrick-Swallow, David J Lockey, Zane B Perkins

Abstract read
In one paragraph

Article in The British journal of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aditi NijhawanLondon's Air Ambulance, London, UK.
Ewoud Ter AvestLondon's Air Ambulance, London, UK.
Callum J TwohigLondon's Air Ambulance, London, UK.
Stacey J WebsterLondon's Air Ambulance, London, UK.
Jared M WohlgemutCentre for Trauma Sciences, Queen Mary University of London, London, UK.ORCID 0000-0001-8276-0465
Jason MorrisLondon's Air Ambulance, London, UK.
Robbie LendrumLondon's Air Ambulance, London, UK.
Virginia Fitzpatrick-SwallowHome Office Registered Forensic Pathologist, Wantage, UK.
David J LockeyLondon's Air Ambulance, London, UK.
Zane B PerkinsLondon's Air Ambulance, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn mature trauma systems, most trauma deaths occur soon after injury yet studies often only include patients who survive to hospital admission. These studies exclude prehospital deaths and introduce substantial survival bias. Understanding trauma fatalities across all phases of care is essential to identify opportunities to further improve trauma outcomes.

methodsThis retrospective cohort study analysed adult trauma fatalities attended by London's Air Ambulance from 1 January 2019 to 31 December 2020. Deaths were classified as prehospital if traumatic cardiac arrest occurred before hospital arrival. Timing of death was recorded as minutes from injury to arrest for prehospital cases and days from admission to death for in-hospital cases. A multidisciplinary panel determined the likely cause of death using clinical, radiological, and post-mortem findings.

resultsAmong 3089 adult trauma patients attended, 497 (16.1%) died. Most deaths (77.1%) occurred prehospital, with a median time from injury to traumatic cardiac arrest of 12 min (i.q.r. 6-24). Haemorrhage and traumatic brain injury accounted for 81.9% of deaths overall, but their distribution differed markedly by phase of care: 96.2% of haemorrhage deaths occurred prehospital, whereas 84.2% of in-hospital deaths were due to traumatic brain injury. In addition, deaths from all other potentially reversible causes, and 95.1% of penetrating trauma deaths, occurred prehospital.

conclusionIn mature trauma systems, most trauma deaths now occur before arrival in hospital, with many due to potentially reversible causes. The greatest opportunities to improve trauma outcomes now lie in the prehospital phase of care.

Indexed as

Emergency Medical ServicesHospital MortalityWounds and InjuriesAdolescentAdultAgedAir AmbulancesCause of DeathFemaleHumansLondonMaleMiddle AgedRetrospective StudiesYoung Adult

Identifiers

PMID41846544
PMCPMC13671401

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.