Evidence map›Paper›PMID 41846457›Full record

ArticleACR open rheumatology2026

Elevated Peripheral CD161

Jiachen Li, Weiyi Xia, Feng Sun, Yingni Li, Yuke Hou, Huanhuan Ren, Xiaolin Sun, Yuhui Li, Zhanguo Li, Tian Liu

Abstract read
In one paragraph

Article in ACR open rheumatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiachen LiDepartment of Rheumatology and Immunology, Peking University People's Hospital and Beijing Key Laboratory for Non-invasive Diagnosis and Immunotherapy of Rheumatic Diseases, Beijing, China.ORCID https://orcid.org/0009-0002-4073-006X
Weiyi XiaDepartment of Rheumatology and Immunology, Peking University People's Hospital and Beijing Key Laboratory for Non-invasive Diagnosis and Immunotherapy of Rheumatic Diseases, Beijing, China.
Feng SunDepartment of Rheumatology and Immunology, Peking University People's Hospital and Beijing Key Laboratory for Non-invasive Diagnosis and Immunotherapy of Rheumatic Diseases, Beijing, China.
Yingni LiDepartment of Rheumatology and Immunology, Peking University People's Hospital and Beijing Key Laboratory for Non-invasive Diagnosis and Immunotherapy of Rheumatic Diseases, Beijing, China.
Yuke HouDepartment of Rheumatology and Immunology, Peking University People's Hospital and Beijing Key Laboratory for Non-invasive Diagnosis and Immunotherapy of Rheumatic Diseases, Beijing, China.ORCID https://orcid.org/0000-0003-2887-4116
Huanhuan RenDepartment of Rheumatology and Immunology, Peking University People's Hospital and Beijing Key Laboratory for Non-invasive Diagnosis and Immunotherapy of Rheumatic Diseases, Beijing, China.
Xiaolin SunDepartment of Rheumatology and Immunology, Peking University People's Hospital and Beijing Key Laboratory for Non-invasive Diagnosis and Immunotherapy of Rheumatic Diseases, Beijing, China.
Yuhui LiDepartment of Rheumatology and Immunology, Peking University People's Hospital and Beijing Key Laboratory for Non-invasive Diagnosis and Immunotherapy of Rheumatic Diseases, Beijing, China.ORCID https://orcid.org/0000-0002-5794-8172
Zhanguo LiDepartment of Rheumatology and Immunology, Peking University People's Hospital and Beijing Key Laboratory for Non-invasive Diagnosis and Immunotherapy of Rheumatic Diseases, Beijing, China.ORCID https://orcid.org/0000-0002-4422-5485
Tian LiuDepartment of Rheumatology and Immunology, Peking University People's Hospital and Beijing Key Laboratory for Non-invasive Diagnosis and Immunotherapy of Rheumatic Diseases, Beijing, China.ORCID https://orcid.org/0000-0002-1691-8372

Funding

Bethune-Puai Medical Research Fund PAYJ-023
6 · The paper itself

Abstract

objectiveBehçet syndrome (BS) is a systemic autoimmune vasculitis characterized by immune dysregulation involving multiple immune cell subsets. CD161

methodsThis prospective multicenter study included 182 patients diagnosed with BS at the three hospitals between 2018 and 2024, 166 patients with systemic lupus erythematosus (SLE) and 149 patients with rheumatoid arthritis (RA) and 114 patients with healthy controls (HCs). Demographic and clinical data were recorded. CD4

resultsPatients with BS had a significantly higher proportion among total Treg cells and CD4

conclusionPatients with BS exhibit an increased CD161

Identifiers

PMID41846457
PMCPMC13093606

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.