Evidence map›Paper›PMID 41846382›Full record

ArticlePhysiological reports2026

Ca

André M Leite-Moreira, João Almeida-Coelho, Inês Falcão-Pires, André P Lourenço, Adelino F Leite-Moreira

Abstract read
In one paragraph

Article in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

André M Leite-MoreiraCardiovascular R&D Centre - UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Porto, Portugal.ORCID 0000-0002-2035-061X
João Almeida-CoelhoCardiovascular R&D Centre - UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Porto, Portugal.
Inês Falcão-PiresCardiovascular R&D Centre - UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Porto, Portugal.
André P LourençoCardiovascular R&D Centre - UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Porto, Portugal.
Adelino F Leite-MoreiraCardiovascular R&D Centre - UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Porto, Portugal.ORCID 0000-0001-7808-3596

Funding

Portuguese Foundation for Science and Technology PTDC/DTP-PIC/4104/2014Portuguese Foundation for Science and Technology UIDB/00051/2020Portuguese Foundation for Science and Technology UIDP/00051/2020
6 · The paper itself

Abstract

The heart constantly adapts to acute hemodynamic load by increasing contractility and stretch-induced compliance (SIC). The latter involves titin phosphorylation, notably by cGMP-dependent protein kinase (PKG). Given that Ca

Indexed as

Calcium-Calmodulin-Dependent Protein Kinase Type 2Cyclic GMP-Dependent Protein KinasesHeartMyocardial ContractionMyocytes, CardiacPapillary MusclesAnimalsMaleMyocardiumPhosphorylationRabbitsRatsRats, WistarCalcium-Calmodulin-Dependent Protein Kinase Type 2Cyclic GMP-Dependent Protein Kinasesdiastolemyocardial compliancemyocardial stiffnessprotein kinasesstretch

Identifiers

PMID41846382
PMCPMC13097467

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.