ArticlePoultry science2026
Oligomeric ultranano hydrogen water improves flock uniformity, antioxidant capacity and intestinal health in growth phase layer-type chickens.
Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Effects of Oligomeric Ultrafine-Nano Hydrogen Water on Laying Performance, Egg Quality, Nutrient Composition, and Intestinal and Reproductive Responses in Late-Laying Hens.Animals : an open access journal from MDPI · 2026Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study evaluated the effects of oligomeric ultranano hydrogen water (OUHW) supplementation on growth performance, immune function, intestinal development, gut microbiota, and metabolic profiles in growing layer-type chickens. A total of 96 healthy chicks were randomly assigned to two treatments (six replicates per treatment, eight birds per replicate): a control group (CON) receiving standard drinking water and an OUHW group, with a 12-week experimental period. OUHW supplementation did not significantly affect average daily feed intake (ADFI), average daily gain (ADG), or feed-to-gain ratio (F/G) (P > 0.05); however, flock uniformity was significantly improved (P < 0.05). No significant differences were observed between treatments in immune organ indices, including the thymus, spleen, and bursa of Fabricius (P > 0.05). Antioxidant capacity was enhanced in the OUHW group, as evidenced by significantly increased serum activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) (P < 0.05), whereas total antioxidant capacity (T-AOC) and malondialdehyde (MDA) levels were not affected (P > 0.05). Furthermore, OUHW supplementation did not significantly alter serum concentrations of immunoglobulin A (IgA), IgG, or IgM, nor jejunal levels of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-2, IL-4, or secretory IgA (P > 0.05). In contrast, ileal villus height (VH) and the villus height-to-crypt depth ratio (VH/CD) were significantly increased in the OUHW group (P < 0.05), indicating improved intestinal development. Cecal microbiota analysis revealed greater microbial richness and diversity in OUHW-treated birds, accompanied by significant shifts in community composition, including enrichment of Firmicutes and Ruminiclostridium (P < 0.05). Metabolomic analysis identified 356 differential metabolites, with enriched pathways related to autophagy, riboflavin metabolism, and vitamin digestion and absorption.
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