Evidence map›Paper›PMID 41845348›Full record

ArticleBMC nursing2026

Prevention and management of radiation dermatitis for patients with nasopharyngeal carcinoma: a best practice implementation project.

Min Hou, Wenhuan Zhong, Kefu Shi, Duoduo Pei, Liping Qi, Binbin Hou, Hui-Xia Feng, Jiali Liu

Abstract read
In one paragraph

Article in BMC nursing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Min Hou *Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, China.
Wenhuan Zhong *Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, China.
Kefu Shi *Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, China.
Duoduo PeiDepartment of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, China.
Liping QiDepartment of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, China.
Binbin HouDepartment of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, China.
Hui-Xia FengDepartment of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, China. fenghx@sysucc.org.cn.
Jiali LiuDepartment of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, China. liujl1@sysucc.org.cn.

Funding

Natural Science Foundation of Guangzhou NO. 2023A04J1775
6 · The paper itself

Abstract

backgroundRadiation dermatitis(RD) is one of the most common acute toxicities of radiotherapy, affecting approximately 85%~95% of patients. Severe RD can substantially impair quality of life and may compromise treatment continuity, thereby reducing the effectiveness of radiotherapy. Despite the availability of clinical guidelines, RD prevention and management in routine practice remain inconsistent.

aimThis best practice implementation project aimed to implement an evidence-based strategies for the prevention and management of RD in patients with nasopharyngeal carcinoma (NPC), improve compliance with best-practice recommendations, and reduce severe RD.

methodsThis was an evidence-based audit and feedback project that used a three-phase approach at a tertiary cancer center in China. We conducted an evidence-based audit-and-feedback project using the JBI Practical Application of Clinical Evidence System (JBI PACES) and Getting Research into Practice (GRiP) framework at a tertiary cancer center in China. Phase 1 involved developing 15 evidence-based audit criteria and conducting a baseline audit (22 patients; 26 nurses). Phase 2 identified barriers to best practice and implemented targeted GRiP-informed strategies. Phase 3 conducted a follow-up audit using the same criteria to evaluate changes in compliance and inform sustainability.

resultsAfter implementation, the incidence of severe RD(≥ Grade Ⅲ) decreased from 9.09%(2/22) to 0% (0/22 cases) at follow up. A comparison between the pre-implementation and post-implementation findings showed significant improvements for all audit criteria, and patients’ compliance with RD management protocol increased to between 59.09% and 100%. Notably, compliance increased from 0% to 100% for system-level criteria (protocol availability and multidisciplinary team establishment) and several key practice criteria.

conclusionsImplementing this evidence-based RD prevention and management program improved practice compliance and reduced severe RD among patients with NPC.

Indexed as

Implementation scienceNasopharyngeal carcinomaQuality improvementRadiation dermatitis

Identifiers

PMID41845348
PMCPMC13107690

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.