Evidence map›Paper›PMID 41845294›Full record

ArticleBMC oral health2026

Dentist-reported practice-related challenges and patient-reported clinical adverse effects following the use of opioid and non-opioid medications to manage acute dental pain following tooth extraction or from toothache.

Deborah E Polk, Alonso Carrasco-Labra, Michelle J Shirey, Olivia Urquhart, Nilesh H Shah

Abstract read
In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Deborah E PolkSchool of Dental Medicine, University of Pittsburgh, 3501 Terrace Street, Suite 6620, Pittsburgh, PA, 15260, USA. dpolk@pitt.edu.
Alonso Carrasco-LabraCenter for Integrative Global Oral Health, Cochrane Oral Health Collaborating Center, School of Dental Medicine, University of Pennsylvania, 240 S. 40th Street, 3rd Floor East, PA, Philadelphia, USA.
Michelle J ShireySchool of Dental Medicine, University of Pittsburgh, 3501 Terrace Street, Suite 6620, Pittsburgh, PA, 15260, USA.
Olivia UrquhartCenter for Integrative Global Oral Health, School of Dental Medicine, University of Pennsylvania, 240 S. 40th Street, 3rd Floor East, Philadelphia, PA, USA.
Nilesh H ShahSchool of Dental Medicine, University of Pittsburgh, 3501 Terrace Street, Suite 6620, Pittsburgh, PA, 15260, USA.

Funding

FDA HHS U01 FD007151Food and Drug Administration (FDA) of the U.S. Department of Health and Human Services U01FD007151
6 · The paper itself

Abstract

backgroundThe purpose of this exploratory study was to describe the types and frequencies of practice-related challenges associated with opioid and non-opioid management of acute dental pain experienced by dentists, such as patients challenging the dentist, requesting a different pain medication, or contacting the dentist after hours for additional pain medication, and clinical adverse effects experienced by patients, such as dizziness or drowsiness.

methodsDentists from across the United States and patients from the U.S. South completed surveys assessing their experience of practice-related challenges and clinical adverse effects. Dentists were eligible if they treated patients for simple or surgical tooth extractions or toothache in a typical month. Patients were eligible if they had obtained treatment from a dentist for a simple or surgical tooth extraction or toothache in the prior two weeks. Data were analyzed using descriptive statistics.

resultsNinety patients and 77 dentists participated in the study. Non-opioid pain medication was taken by 73 (81%) patients; opioid medication was taken by 2 (2%) patients; and 15 (16.7%) patients took no pain medication. Less than 3% of patients reported experiencing clinical adverse effects, and those experienced were generally mild. Opioids were never prescribed by 29 (37.7%) dentists; and opioids were prescribed by (62.3%) dentists. Over 80% of dentists reported practice-related challenges; however, 92% of those who experienced practice-related challenges reported that they occurred with fewer than half their patients. Over 31% of dentists who do not prescribe opioids reported never experiencing practice-related challenges compared with 10.4% of dentists who do prescribe opioids, [Formula: see text](1) = 5.17; p = .02.

conclusionsIn this exploratory study, few patients experienced clinical adverse effects from the pharmacologic management of acute dental pain regardless of the diagnosis, procedure, or pharmacologic management approach adopted. Dentists who prescribed opioids experienced practice-related challenges more frequently than dentists who do not prescribe opioids. Future research should determine whether by switching from opioid to non-opioid-containing medication, dentists are able to reduce the practice-related challenges they experience without increasing the clinical adverse effects their patients experience.

Indexed as

Acute PainAnalgesics, Non-NarcoticAnalgesics, OpioidPractice Patterns, Dentists'ToothacheTooth ExtractionAdultAgedDentistsFemaleHumansMaleMiddle AgedUnited StatesAnalgesics, Non-NarcoticAnalgesics, OpioidAcute dental painAnalgesics, Non-NarcoticAnalgesics, OpioidDentistsHealthcare surveys, Self-reportPatients, adverse effects

Identifiers

PMID41845294
PMCPMC13107633

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.