Evidence map›Paper›PMID 41845292›Full record

ArticleBMC geriatrics2026

The association between executive function and eye-hand coordination in older adults: the partial mediation of attention, global cognition, and muscle strength.

Tiecheng Wu, Shujing Lei, Jialin Chen, Minguang Yang, Hong Liu, Jingsong Wu, Youze He

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Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Tiecheng WuThe Institute of Rehabilitation Industry, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, Fujian, China.
Shujing LeiThe College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, Fujian, China.
Jialin ChenThe College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, Fujian, China.
Minguang YangThe Institute of Rehabilitation Industry, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, Fujian, China.
Hong LiuThe Institute of Rehabilitation Industry, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, Fujian, China.
Jingsong WuThe Institute of Rehabilitation Industry, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, Fujian, China. jingsongwu01@163.com.
Youze HeThe Institute of Rehabilitation Industry, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, Fujian, China. 2190910010@fjtcm.edu.cn.

Funding

Major Scientific and Technological Innovative Talents Training Project of Fujian University of Traditional Chinese Medicine XJB2022006the Natural Science Foundation of Fujian Province 2023J05174the Rehabilitation Technology Innovation Center by Joint Collaboration of Ministry of Education and Fujian Province, Fujian University of Traditional Chinese Medicine X2023002the Young Scientific and Technological Innovative Talents Training Project of Fujian University of Traditional Chinese Medicine XQC2023004
6 · The paper itself

Abstract

backgroundEye‒hand coordination (EHC) integrates cognitive and motor processes and is important for daily functions in older adults. Poor EHC performance is often associated with a decline in cognitive function, namely, executive function and attention, as well as a decline in motor function. However, their relationship remains unclear.

objectiveTo examine the associations among executive function, attention, global cognition, muscle strength, and EHC performance in elderly individuals.

methodsIn this cross-sectional study, 213 community-dwelling older adults (median age 71 years, IQR 65.5–76.0) underwent assessments of executive function (Shape Trail Test Part B, STT-B), attention (Digit Cancellation Test, DCT), global cognition (Montreal Cognitive Assessment, MoCA), EHC reaction time and accuracy (EHC-RT, EHC-ACC), right shoulder flexion strength (rSFS), and right hand grip strength (rGS). Mediation analyses were conducted via PROCESS Model 4 with 5,000 bootstrap resamples (95% CI).

resultsSTT-B score was associated with EHC-RT (ρ = 0.32, p < 0.001) and remained an independent predictor of EHC-RT (β = 0.17, p = 0.03) after adjusting for other variables in a linear regression model. Significant indirect effects of STT-B on EHC-RT were observed via DCT (β = 0.09, 95% CI [0.03, 0.17]; 23.50% of the total effect), MoCA (β = 0.18, 95% CI [0.08, 0.30]; 49.73%) and rSFS (β = 0.05, 95% CI [0.01, 0.10]; 13.11%). Chain mediation analysis revealed a serial association from the STT-B via DCT and the MoCA to the EHC-RT (β = 0.03, 95% CI [0.00, 0.06]). Direct effect remained significant.

conclusionExecutive function was associated with EHC-RT, with attention, global cognition, and shoulder flexion strength acting as partial statistical mediators. Longitudinal or interventional studies are needed to test causal pathways.

trial registrationChinese Clinical Trial Registration Center, No. ChiCTR2300073086. Registration date: June 30, 2023. https://www.chictr.org.cn/ .

Indexed as

AttentionCognitionExecutive FunctionHandMuscle StrengthPsychomotor PerformanceAgedCross-Sectional StudiesFemaleHand StrengthHumansMaleCognitive functionEye-hand coordinationMediation analysisMuscle strengthOlder adults

Identifiers

PMID41845292
PMCPMC13107846

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.