Evidence map›Paper›PMID 41845249›Full record

ArticleBMC geriatrics2026

Prehabilitation as a litmus test for surgery in frail nonagenarians: a case series.

Andrew Milks, Mirana Rakotoarivony, Nicole Saur, Chelsia Gillis

Abstract readCase Reports
In one paragraph

Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew MilksSchool of Human Nutrition, McGill University, Macdonald Campus, 21111 Lakeshore, Ste-Anne-de-Bellevue, QC, H9X 3V9, Canada.
Mirana RakotoarivonyResearch Institute, McGill University Health Centre, Montreal, Canada.
Nicole SaurDepartment of Surgery, University of Pennsylvania, Philadelphia, USA.
Chelsia GillisSchool of Human Nutrition, McGill University, Macdonald Campus, 21111 Lakeshore, Ste-Anne-de-Bellevue, QC, H9X 3V9, Canada. chelsia.gillis@mcgill.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs more older adults undergo major elective surgery, frailty increases their risk of complications. Prehabilitation, which often combines nutrition, exercise, and psychosocial support, may benefit these patients by improving their physiological reserve and increasing their resilience for recovery. However, representation of very old adults in prehabilitation research is scarce. CASE PRESENTATION: This case series presents the unique experiences of five nonagenarians who participated in prehabilitation prior to major elective surgery for colorectal cancer. Two patients received nutrition-only interventions, two received combined nutrition and exercise interventions, and one received exercise alone. Two patients who improved in both preoperative nutritional and functional status experienced favourable perioperative outcomes. In contrast, three patients demonstrated a decline in functional status accompanied by postoperative complications; one of these patients also experienced a decline in nutritional status and subsequently died.

conclusionWe highlight that, among nonagenarians with frailty, prehabilitation performance may be associated with postoperative outcomes, suggesting that responsiveness to prehabilitation may serve as a pragmatic indicator of surgical readiness. Prehabilitation provides an opportunity to assess physiological reserve and guide shared decision-making regarding surgical candidacy and perioperative care intensity.

Indexed as

Colorectal NeoplasmsElective Surgical ProceduresFrail ElderlyFrailtyPostoperative ComplicationsPreoperative CarePreoperative ExerciseAged, 80 and overFemaleHumansMaleNutritional StatusColorectal cancerElderlyFrailtyFunctional capacityMalnutritionNutritionPrehabilitationSurgery

Identifiers

PMID41845249
PMCPMC13107882

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.