Evidence map›Paper›PMID 41845157›Full record

ArticleOdontology2026

Comparative analysis of postoperative mechanical behavior of immature premolars: apexification vs regeneration.

Ana Carolina da Silva, Fernando César de Barros Faria Júnior, Gustavo Guimarães Guerrero, Alexandre Luiz Souto Borges, Marcia Carneiro Valera

Abstract readComparative Study
In one paragraph

Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana Carolina da SilvaDepartment of Dental Materials and Prosthodontics, Institute of Science and Technology, Sao Paulo State University (UNESP), Engenheiro Francisco Jose Longo Avenue, 777 - Sao Jose Dos Campos, Sao Paulo, 12245-000, Brazil.ORCID http://orcid.org/0000-0001-7811-7792
Fernando César de Barros Faria JúniorDepartment of Restorative Dentistry, Endodontic Division, Institute of Science and Technology, São Paulo State University - UNESP, São José Dos Campos, Sao Paulo, Brazil.ORCID http://orcid.org/0009-0002-6170-6798
Gustavo Guimarães GuerreroDepartment of Restorative Dentistry, Endodontic Division, Institute of Science and Technology, São Paulo State University - UNESP, São José Dos Campos, Sao Paulo, Brazil.ORCID http://orcid.org/0000-0003-1163-5530
Alexandre Luiz Souto BorgesDepartment of Dental Materials and Prosthodontics, Institute of Science and Technology, Sao Paulo State University (UNESP), Engenheiro Francisco Jose Longo Avenue, 777 - Sao Jose Dos Campos, Sao Paulo, 12245-000, Brazil.ORCID http://orcid.org/0000-0002-5707-7565
Marcia Carneiro ValeraDepartment of Restorative Dentistry, Endodontic Division, Institute of Science and Technology, São Paulo State University - UNESP, São José Dos Campos, Sao Paulo, Brazil. marcia@fosjc.unesp.br.ORCID http://orcid.org/0000-0001-7398-6438

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To compare the mechanical behavior of lower premolars with incomplete root formation treated by apexification and regeneration and assess revascularization's impact on dentin thickness using finite element analysis. A mandibular bone model was obtained from a computed tomography scan and modeled using the CAD Rhinoceros 7.0 software program. The models were composed of enamel, dentin, pulp, periodontal ligament, cortical bone, medullary bone, gutta-percha, MTA, blood clot, and composite resin. The study groups were: IT (Intact Tooth); AC (Accessed Tooth); R (revascularization); and AX (apexification). After modeling the structures, the geometries were exported to the Ansys 13.0 finite element analysis software program. The models were submitted to loads of 200 N on the distal sulcus of the occlusal surface. The loading was directed at 45° to the occlusal plane. The results were calculated and qualitatively analyzed using displacement maps and maximum principal stress. The apexification models supported lower compressive and tensile stresses when compared to the revascularization models. Revascularization reduced stress concentration in the periradicular tissues, whereas apexification resulted in lower tensile stress in coronal dentin.

Indexed as

ApexificationBicuspidRegenerationBiomechanical PhenomenaDental Stress AnalysisFinite Element AnalysisHumansStress, MechanicalApexificationFinite element analysisMTARegenerative endodonticsRoot canal treatment

Identifiers

PMID41845157
PMCPMC13631037

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.