Evidence map›Paper›PMID 41845084›Full record

ArticleTechniques in coloproctology2026

Development of a convolutional neural network for the endoscopic classification of pouchitis in patients after restorative proctocolectomy.

M Saifi, U Eisenmann, F Ringwald, R Liu, P Kienle, D Schmitz

Registry-linked trialAbstract read
In one paragraph

Article in Techniques in coloproctology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04864587 (Artificial Intelligence in Image Recognition of Pouchoscopies in Patients With Restorative Proctocolectomy), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04864587 completednot on this map

Artificial Intelligence in Image Recognition of Pouchoscopies in Patients With Restorative Proctocolectomy

TypeobservationalSponsorTheresienkrankenhaus und St. Hedwig-Klinik GmbHRan2021 to 2023Enrolled500ConditionsPouches, IleoanalArmsArtificial intelligence used for image recognition in pouchoscopy
3 · Its place in the literature

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M Saifi *Department of General and Visceral Surgery, Brüderklinikum Julia Lanz - Diako Mannheim, Speyerer Straße 91-93, 68163, Mannheim, Germany. M.Saifi@bbtgruppe.de.
U Eisenmann *Institute of Medical Informatics, Heidelberg University, Heidelberg, Germany.
F RingwaldInstitute of Medical Informatics, Heidelberg University, Heidelberg, Germany.
R LiuInstitute of Medical Informatics, Heidelberg University, Heidelberg, Germany.
P Kienle *Department of General and Visceral Surgery, Brüderklinikum Julia Lanz - Diako Mannheim, Speyerer Straße 91-93, 68163, Mannheim, Germany.
D Schmitz *Department of Gastroenterology, Helios Kliniken Schwerin, Schwerin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThe aim of this prospective single-center study is to train convolutional neural networks (CNNs) to detect the presence of pouchitis in two-dimensional (2D) images acquired during pouchoscopies and test its feasibility.

methodsTwo separate networks were constructed. The goal of network 1 was to detect whether an inflammation was present. Network 2 was designed to classify endoscopic findings of pouchitis, according to the pouchitis disease activity index (PDAI) score. The dataset was divided into three distinct sets: a training set, a validation set, and a test set. The performance was quantified using a tenfold cross-validation approach.

resultsFor the detection of inflammation, sensitivity was 71.78% with a specificity of 90.35%. When differentiating the six endoscopic findings according to the PDAI score, the sensitivity ranged from a low of 38% for the 'ulceration' class to a high of 67.18% for the 'friability' class, with a specifity of 94.12% ('ulceration') and 96.57% ('friability').

conclusionsThis study shows that an artificial, intelligence-based image recognition software can be trained to recognize the endoscopic features of pouchitis with reasonable accuracy. The results, although encouraging, confirm that artificial intelligence (AI) performance in this context remains below human expert level. A larger dataset, human benchmarking and more appropriate endoscopic markers are required to reach clinically relevant performance. Trial registration This trial was registered in the 'ClinicalTrials.gov' database on 26 April 2021 (NCT04864587).

Indexed as

Convolutional Neural NetworksNeural Networks, ComputerPouchitisProctocolectomy, RestorativeAdultFeasibility StudiesFemaleHumansMaleProspective StudiesSensitivity and SpecificityConvolutional neural networksEndoscopyInflammatory bowel diseasePouchitis

Identifiers

PMID41845084
PMCPMC13002692

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