Evidence map›Paper›PMID 41845081›Full record

ArticleAesthetic plastic surgery2026

From Serum to Surgery: The Significance of Albumin in Preoperative Risk Stratification-An Analysis of 200,015 Plastic Surgery Patients.

Michael Alfertshofer, Samuel Knoedler, P Niclas Broer, Philipp Moog, Hans-Günther Machens, Konstantin Frank, Leonard Knoedler, Max Heiland, Carsten Rendenbach, Steffen Koerdt and 3 more

Abstract read
In one paragraph

Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Michael AlfertshoferDepartment of Plastic and Hand Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany. michaelalfertshofer@gmx.de.ORCID 0000-0002-4892-2376
Samuel KnoedlerDepartment of Plastic and Hand Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
P Niclas BroerDepartment of Plastic, Hand and Burn Surgery, Klinikum Bogenhausen, Technical University Munich, Munich, Germany.
Philipp MoogDepartment of Plastic and Hand Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Hans-Günther MachensDepartment of Plastic and Hand Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Konstantin FrankDepartment of Plastic, Hand and Reconstructive Surgery, University Hospital Regensburg, Regensburg, Germany.
Leonard KnoedlerDepartment of Oral and Maxillofacial Surgery, Charité Universitätsmedizin Berlin, Berlin, Germany.
Max HeilandDepartment of Oral and Maxillofacial Surgery, Charité Universitätsmedizin Berlin, Berlin, Germany.
Carsten RendenbachDepartment of Oral and Maxillofacial Surgery, Charité Universitätsmedizin Berlin, Berlin, Germany.
Steffen KoerdtDepartment of Oral and Maxillofacial Surgery, Charité Universitätsmedizin Berlin, Berlin, Germany.
Dennis P OrgillDivision of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Gabriel HundeshagenDepartment of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, University of Heidelberg, 67071, Ludwigshafen, Germany.
Adriana C PanayiDepartment of Oral and Maxillofacial Surgery, Charité Universitätsmedizin Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlastic and reconstructive surgery (PRS) encompasses a wide range of procedures, and postoperative complications remain a persistent challenge. While preoperative laboratory values (PLVs) are routinely assessed, their predictive value for postoperative outcomes in PRS is unclear. This study evaluates the association between PLVs and postoperative morbidity to enhance risk stratification.

methodsThe ACS-NSQIP database (2008-2022) was analyzed for PRS patients. PLVs included sodium, blood urea nitrogen, creatinine, albumin, bilirubin, SGOT, alkaline phosphatase, white blood cell count, hematocrit, platelets, partial thromboplastin time, international normalized ratio, and prothrombin time (PT). Multivariate logistic regression identified independent predictors of complications, while decision tree analysis established risk thresholds, validated through cross-validation.

resultsA total of 200,015 patients with a mean age of 50.3±14.5 years and a mean BMI of 29.1±6.8 kg/m

conclusionAlbumin and PT are key predictors of 30-day postoperative complications in PRS. Preoperative optimization of these values can enhance patient safety and surgical outcomes. Findings support integrating targeted preoperative evaluations into clinical practice. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Plastic Surgery ProceduresPostoperative ComplicationsSerum AlbuminAdultAgedDatabases, FactualFemaleHumansMaleMiddle AgedPredictive Value of TestsPreoperative CareRetrospective StudiesRisk AssessmentRisk FactorsSerum AlbuminAlbuminComplication managementLaboratory valuesRisk stratificationRoutine examination

Identifiers

PMID41845081
PMCPMC13183695

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.