Evidence map›Paper›PMID 41845062›Full record

ArticleNature genetics2026

Breeding ideotype maize with enhanced yield through genomics-guided pyramiding of favorable alleles.

Wen Yao, Lixia Ku, Baobao Wang, Zhenzhen Ren, Huihui Su, Chengwei Li, Huafeng Liu, Haixia Zeng, Zhixue Liu, Dongling Zhang and 11 more

Abstract read
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In one paragraph

Article in Nature genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Wen Yao *State Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.ORCID http://orcid.org/0000-0002-0643-506X
Lixia Ku *State Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Baobao Wang *Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID http://orcid.org/0000-0001-5615-7910
Zhenzhen Ren *State Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Huihui SuState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Chengwei LiState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Huafeng LiuState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Haixia ZengState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Zhixue LiuState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Dongling ZhangState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Yazhou WangCollege of Life Sciences, Henan Agricultural University, Zhengzhou, China.
Xinle ZhuBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Qiannan ZhaoState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Xiaomeng HuState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Chongyu SunState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Shengbo HanState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Jiafa ChenCollege of Life Sciences, Henan Agricultural University, Zhengzhou, China.
Miaomiao BaoState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Tianyi LiState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China.
Haiyang WangCollege of Life Sciences, State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, Guangzhou, China. wanghaiyang@yzwlab.cn.ORCID http://orcid.org/0000-0002-1302-5747
Yanhui ChenState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, College of Agronomy, Henan Agricultural University, Zhengzhou, China. chenyanhui@henau.edu.cn.ORCID http://orcid.org/0000-0002-5163-1393

Funding

National Natural Science Foundation of China (National Science Foundation of China) 31230055
6 · The paper itself

Abstract

Breeding ideotype maize for high-density planting is crucial for increasing yield but is hindered by a limited understanding of plant architecture regulation. Here we uncover a prominent role for the accumulation of homozygous favorable alleles in genes regulating four principal shoot traits constituting a maize ideotype, and we identify and functionally validate eight architecture-regulating genes. Guided by genomics, we selected the elite hybrid Yufeng303 as a chassis to develop five improved parental lines by pyramiding favorable alleles of these eight genes together with genome-wide loci associated with these traits. These improved parental lines led to the creation of four new hybrids better suited for high-density planting, achieving 4.1-9.2% higher plot yields than Yufeng303 across eight environments. This study exemplifies the power of genomics-guided breeding of ideotype maize for high densities and serves as a template for informed hybrid improvement of other appropriate crops.

Indexed as

GenomicsPlant BreedingZea maysAllelesGenes, PlantGenome, PlantPhenotypeQuantitative Trait Loci

Identifiers

PMID41845062

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.