Evidence map›Paper›PMID 41844980›Full record

ArticleActa neurochirurgica2026

Endoscopic transnasal approach to pterygopalatine fossa and infratemporal fossa: case series utilizing endoscopic modified medial maxillectomy (EMMM)/direct approach to the anterior and lateral part of the maxillary sinus (DALMA).

Motoyuki Umekawa, Hirotaka Hasegawa, Yuki Shinya, Masahiro Shin, Kenji Kondo, Satoru Miyawaki, Nobuhito Saito

Abstract read
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Article in Acta neurochirurgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Motoyuki UmekawaDepartment of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan.ORCID 0000-0002-7722-9861
Hirotaka HasegawaDepartment of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan. hirotaka.hasegawa@ymail.ne.jp.ORCID 0000-0002-3585-2188
Yuki ShinyaDepartment of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan.ORCID 0000-0003-0097-5804
Masahiro ShinDepartment of Neurosurgery, Teikyo University Hospital, Tokyo, Japan.ORCID 0000-0001-8025-127X
Kenji KondoDepartment of Otorhinolaryngology and Head and Neck Surgery, The University of Tokyo Hospital, Tokyo, Japan.ORCID 0000-0002-0496-5067
Satoru MiyawakiDepartment of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan.ORCID 0000-0001-6369-3391
Nobuhito SaitoDepartment of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan.ORCID 0000-0001-9756-781X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoscopic transnasal surgery (ETS) has become an established treatment for skull base lesions; however, its lateral reach to the pterygopalatine fossa (PPF) and infratemporal fossa (ITF) remains limited due to restricted maneuverability within the nasal corridor. To address this limitation, the endoscopic modified medial maxillectomy (EMMM) and the direct approach to the anterior and lateral part of the maxillary sinus (DALMA) provides lateral access through the maxillary sinus. This study evaluated the technical feasibility and outcomes of ETS combining EMMM and DALMA.

methodA retrospective review was conducted on five patients (January 2021-April 2024) who underwent ETS involving EMMM and/or DALMA. Surgical trajectory, extent of resection, and postoperative outcomes were analyzed. EMMM preserved nasolacrimal duct and opened the medial maxillary wall for direct access to the PPF and ITF. In DALMA, submucosal dissection was extended laterally beyond the piriform aperture to remove the anterior maxillary wall creating as an additional port complementary to EMMM.

resultsTwo patients (trigeminal schwannoma, idiopathic cerebrospinal fluid leak) underwent EMMM alone, and three patients (meningiomas extending to the ITF/PPF) underwent combined EMMM and DALMA. The dual-portal configuration provided separate working corridors for the endoscope and instruments. This arrangement minimized mutual interference and improved surgical maneuverability, allowing exposure of the lateral skull base up to the medial border of the mandible. Gross or subtotal resection was achieved in all cases. Postoperative complications were minimal; one patient experienced slight worsening of facial numbness, and one experienced slight numbness in the upper lip, likely due to DALMA-induced injury of the anterior superior alveolar nerve.

conclusionsCombining EMMM and DALMA approaches provides a safe and minimally invasive option for treating lesions extending laterally into the ITF and PPF. Dual-portal configuration appears to improve instrument maneuverability and facilitate more extensive resection, thereby potentially expanding the applicability of ETS.

Indexed as

Infratemporal FossaMaxillary SinusNatural Orifice Endoscopic SurgeryPterygopalatine FossaSkull Base NeoplasmsAdultAgedEndoscopyFemaleHumansMaleMiddle AgedNeuroendoscopyRetrospective StudiesDirect approach to the anterior and lateral part of the maxillary sinusEndoscopic modified medial maxillectomyEndoscopic transnasal surgeryInfra-temporal fossaPterygopalatine fossaSkull base

Identifiers

PMID41844980
PMCPMC12999672

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