Evidence map›Paper›PMID 41844834›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Trends in admissions and costs for neonatal intensive care in US children's hospitals, 2017-2022.

Ashlee J Vance, Troy Richardson, Brian King, Joanne Lagatta, Kuan-Chi Lai, Ashwini Lakshmanan, Henry C Lee, Tamorah Lewis, Ravi M Patel, Joseph G Kohne

Abstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ashlee J VanceCenter for Health Policy and Health Services Research, Henry Ford Health, Detroit, MI, USA. avance2@hfhs.org.ORCID http://orcid.org/0000-0003-0284-3995
Troy RichardsonChildren's Hospital Association, Lenexa, KS, USA.
Brian KingDepartment of Pediatrics, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0009-0000-6959-8969
Joanne LagattaDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID http://orcid.org/0000-0002-5147-2396
Kuan-Chi LaiDivision of Neonatology, Children's Hospital Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-0885-468X
Ashwini LakshmananDepartment of Health Systems Science, Bernard J. Tyson Kaiser Permanente School of Medicine, Pasadena, CA, USA.ORCID http://orcid.org/0000-0001-8259-1905
Henry C LeeDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-8383-1720
Tamorah LewisDepartment of Paediatrics, University of Toronto Temerty Faculty of Medicine, Toronto, ON, USA.ORCID http://orcid.org/0000-0003-2137-8339
Ravi M PatelDepartment of Pediatrics, Emory University, Children's Healthcare of Atlanta, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-7444-5550
Joseph G KohneSchool of Medicine, Case Western Reserve Univeristy, Cleveland, OH, USA.ORCID http://orcid.org/0000-0001-9978-2759

Funding

CTSA K12 Program at the University of MichiganK12TR004374 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VICKI L ELLINGROD, Leah Elizabeth Robinson · 2023 to 2026
$6.5M
Henry Ford Health System Internal Mentored AwardU.S. Department of Health & Human Services | National Institutes of Health (NIH) K12TR004374
6 · The paper itself

Abstract

objectivesTo evaluate trends in neonatal intensive care unit (NICU) admissions, illness acuity, and hospitalization costs among U.S. children's hospitals from 2017 to 2022.

methodsThis retrospective cohort study used data from the Pediatric Health Information System (PHIS) and included all NICU admissions. We examined trends in patient characteristics (e.g., gestational age, complex chronic conditions), illness severity scores, and standardized hospital costs. Interrupted time series analyses assessed changes in NICU costs over time.

resultsThere were 234,571 infants admitted to NICUs in US children's hospitals between 2017 and 2022. NICU admissions shifted significantly by gestational age with admissions increasing by 10-18% among extremely, very, and late preterm infants. Term infants remained the largest admission group, averaging 45% annually (p < 0.001). Infants with ≥1 complex chronic condition increased from 46.6% in 2017 to 50.9% in 2022 (p < 0.001). NICU-specific illness severity increased modestly over time (1.14-1.24, p < 0.001). Median standardized NICU hospital costs rose by approximately 20% over the study period, with notable inflections in early 2020 and 2021.

conclusionsAmong US children's hospitals in the PHIS database, NICU admissions were increasingly complex and costly. These findings highlight the importance of ongoing monitoring of resource use and patient mix in specialized NICU settings.

Indexed as

Hospital CostsHospitalizationHospitals, PediatricIntensive Care Units, NeonatalPatient AdmissionFemaleGestational AgeHumansInfantInfant, NewbornInfant, PrematureMaleRetrospective StudiesSeverity of Illness IndexUnited States

Identifiers

PMID41844834
PMCPMC13290482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.