Evidence map›Paper›PMID 41844652›Full record

ArticleNature communications2026

Proton channels govern vesicular carbonate chemistry in mineralizing cells of a marine calcifier.

Sima Jonusaite, Catrin Przibylla-Diop, Marianne Musinszki, Ornina Merza, Marcus Schewe, Thomas Baukrowitz, Marian Y Hu

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sima JonusaiteInstitute of Physiology, Kiel University, Kiel, Germany.
Catrin Przibylla-DiopInstitute of Physiology, Kiel University, Kiel, Germany.
Marianne MusinszkiInstitute of Physiology, Kiel University, Kiel, Germany.ORCID 0000-0002-5597-6735
Ornina MerzaInstitute of Physiology, Kiel University, Kiel, Germany.
Marcus ScheweInstitute of Physiology, Kiel University, Kiel, Germany.ORCID 0000-0002-6192-5651
Thomas BaukrowitzInstitute of Physiology, Kiel University, Kiel, Germany.ORCID 0000-0003-4562-0505
Marian Y HuInstitute of Physiology, Kiel University, Kiel, Germany. m.hu@physiologie.uni-kiel.de.ORCID 0000-0002-8914-139X

Funding

EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 101085894European Research Council
6 · The paper itself

Abstract

Biomineralization shapes the geology of our planet and is an integral part of the global carbon cycle. Many calcifying organisms generate biomineral precursors within their cells but the mechanisms controlling carbonate chemistry in the calcifying vesicles remain unknown. Using the sea urchin embryo that is a prime model for biomineralization by intracellular amorphous calcium carbonate (ACC) formation this work demonstrated a high proton permeability of the calcifying cells and their vesicles. Intra-vesicular pH and Ca

Indexed as

BiomineralizationCalcification, PhysiologicCalcium CarbonateIon ChannelsProtonsSea UrchinsAnimalsCalciumHydrogen-Ion ConcentrationMembrane PotentialsCalciumCalcium CarbonateIon ChannelsProtons

Identifiers

PMID41844652
PMCPMC13000164

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.