Evidence map›Paper›PMID 41844620›Full record

ArticleNature communications2026

Bidirectional regulation of social memory by two distinct types of GABAergic neurons in the lateral septum.

Li Zhang, Mengbing Huang, Chao-Liang Ye, Zhiwei Tang, Mingrui Xu, Yuan Wang, Ting Wang, Shu Luo, Rui Ji, Chang Yu and 4 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Li Zhang *Department of Physiology, School of Basic Medicine and Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Mengbing Huang *Department of Physiology, School of Basic Medicine and Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chao-Liang Ye *Department of Physiology, School of Basic Medicine and Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhiwei TangDepartment of Physiology, School of Basic Medicine and Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Mingrui XuDepartment of Neurology, The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Yuan WangDepartment of Physiology, School of Basic Medicine and Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ting WangState Key Laboratory of Molecular Development Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Shu LuoDepartment of Physiology, School of Basic Medicine and Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Rui JiDepartment of Physiology, School of Basic Medicine and Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chang YuDepartment of Physiology, School of Basic Medicine and Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hongyan LuoDepartment of Physiology, School of Basic Medicine and Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Peng CaoNational Institute of Biological Sciences, Beijing, China.ORCID http://orcid.org/0000-0001-7739-6857
Qing-Feng WuState Key Laboratory of Molecular Development Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0003-3272-6247
Man JiangDepartment of Physiology, School of Basic Medicine and Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. manjiang@hust.edu.cn.ORCID http://orcid.org/0000-0002-0470-8722

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32271197National Natural Science Foundation of China (National Science Foundation of China) 32471013National Natural Science Foundation of China (National Science Foundation of China) 82161138025
6 · The paper itself

Abstract

Humans and animals memorize and recognize familiar conspecifics during social interactions, known as social memory. While the hippocampus is crucial for social memory, the dynamic regulation of social memory remains unclear. Here, using male mice, we identified two molecularly distinct subpopulations of GABAergic neurons in the mouse lateral septum (LS) expressing somatostatin (SST) and calbindin 1 (CB), respectively, with complementary distribution patterns. Activation of SST

Indexed as

GABAergic NeuronsMemorySeptal NucleiSocial BehaviorAnimalsCalbindinsMaleMiceMice, Inbred C57BLOptogeneticsSomatostatinCalbindinsSomatostatin

Identifiers

PMID41844620
PMCPMC13272675

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.