Evidence map›Paper›PMID 41844555›Full record

ArticleBritish journal of haematology2026

Real-world evidence supports the safety and efficacy profile of luspatercept in clinically complex and heavily iron-overloaded patients.

Barbara Gianesin, Antonietta Zappu, Giovanni Battista Ferrero, Carmen Maria Gaglioti, Michele Santodirocco, Giuseppe Fania, Giovanna Graziadei, Daniele Lello Panzieri, Antonella Massa, Tommaso Mina and 20 more

Abstract read
In one paragraph

Article in British journal of haematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Barbara GianesinFORANEMIA ETS Foundation, Genoa, Italy.ORCID https://orcid.org/0009-0003-4326-4559
Antonietta ZappuS.C. Centro delle Microcitemie e Anemie Rare, ARNAS G. Brotzu, Cagliari, Italy.
Giovanni Battista FerreroThalassemia and Rare Hematological Diseases Centre, San Luigi Gonzaga University Hospital, Orbassano (Torino), Italy.ORCID https://orcid.org/0000-0002-3793-5788
Carmen Maria GagliotiThalassemia and Rare Hematological Diseases Centre, San Luigi Gonzaga University Hospital, Orbassano (Torino), Italy.
Michele SantodiroccoDay Hospital Thalassemia, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo (FG), Italy.ORCID https://orcid.org/0000-0002-0032-5628
Giuseppe FaniaImmunoematologia e Medicina Trasfusionale (SIMT), IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo (FG), Italy.
Giovanna GraziadeiFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, SC Medicina ad Indirizzo Metabolico, Milan, Italy.
Daniele Lello PanzieriUniversità degli Studi di Milano, Milan, Italy.ORCID https://orcid.org/0000-0003-2578-3550
Antonella MassaServizio Trasfusionale, Ospedale "Giovanni Paolo II", Olbia, Italy.
Tommaso MinaPediatric Hematology/Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Francesca PoleseU.O. Medicina Trasfusionale, Ospedale dell'Angelo, Azienda ULSS 3 Serenissima, Mestre, Venice, Italy.
Angelantonio VitucciHematology and Bone Marrow Transplantation Unit, AOUC Policlinico, Bari, Italy.
Francesco ArcioniPediatric Oncology-Hematology Unit, Santa Maria della Misericordia Hospital, Perugia, Italy.
Maria Caterina PuttiClinic of Pediatric Hematology Oncology, Department of Women's and Children's Health, University Hospital of Padua, Padua, Italy.
Valerio CecinatiU.O.C. di Pediatria Oncoematologia Pediatrica e Microcitemia, Ospedale Santissima Annunziata, Taranto, Italy.
Ilaria FotziU.O.C. "Oncologia, Ematologia e Trapianto di Cellule Staminali Emopoietiche", Meyer Children's Hospital IRCCS, Florence, Italy.
Paola Maria Grazia SannaServizio Trasfusionale Aziendale, Azienda Ospedaliero-Universitaria di Sassari, Sassari, Italy.
Antonio CappelloASL Novara-Ospedale Ss. Trinità, Borgomanero, Novara, Italy.
Filomena LongoU.O.C. Talassemie ed Emoglobinopatie, Azienda Ospedaliero Universitaria S. Anna, Ferrara, Italy.
Roberto LisiThalassemia Unit, ARNAS Garibaldi, Catania, Italy.
Annamaria PasanisiU.O.S. Centro Microcitemia "A. Quarta"-U.O.C. Ematologia PO Perrino, Brindisi, Italy.
Daniela PietrasantaDivision of Hematology, Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.
Monica BocchiaDepartment of Medical Science, Surgery and Neuroscience, Hematology, University of Siena, Siena, Italy.
Elisa BertoniU.O. Oncoematologia Pediatrica e Trapianto di Midollo Osseo, ASST Spedali Civili di Brescia, Brescia, Italy.
Antonella CossuCentro Microcitemie, Presidio Ospedaliero San Francesco, Nuoro, Italy.
Marilena SerraInternal Medicine Unit, Thalassemia Centre, "Fazzi" Hospital, Lecce, Italy.
Susanna BarellaS.C. Centro delle Microcitemie e Anemie Rare, ARNAS G. Brotzu, Cagliari, Italy.
Antonia GiganteFORANEMIA ETS Foundation, Genoa, Italy.
Gian Luca ForniFORANEMIA ETS Foundation, Genoa, Italy.
Raffaella OrigaS.C. Centro delle Microcitemie e Anemie Rare, ARNAS G. Brotzu, Cagliari, Italy.ORCID https://orcid.org/0000-0002-2346-9616

Funding

Bristol-Myers Squibb Services Unlimited
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

extramedullary haematopoiesisluspaterceptreal‐world settingthromboembolismtransfusion‐dependent thalassaemia

Identifiers

PMID41844555
PMCPMC13267453

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.