Evidence map›Paper›PMID 41844333›Full record

ArticleThe Laryngoscope2026

Symptom Outcomes After Septal Perforation Surgical Repair Versus 3D-Printed Customized Prosthesis.

Pedro Lança Gomes, Nitish Kumar, Stephen F Bansberg, Michael J Marino, Devyani Lal, Amar Miglani

Abstract readComparative Study
In one paragraph

Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pedro Lança GomesDepartment of Otorhinolaryngology, Mayo Clinic in Arizona, Phoenix, Arizona, USA.ORCID 0000-0002-6422-5271
Nitish KumarDepartment of Otorhinolaryngology, Mayo Clinic in Arizona, Phoenix, Arizona, USA.ORCID 0000-0001-9923-9254
Stephen F BansbergDepartment of Otorhinolaryngology, Mayo Clinic in Arizona, Phoenix, Arizona, USA.
Michael J MarinoDepartment of Otorhinolaryngology, Mayo Clinic in Arizona, Phoenix, Arizona, USA.ORCID 0000-0002-8672-0310
Devyani LalDepartment of Otorhinolaryngology, Mayo Clinic in Arizona, Phoenix, Arizona, USA.ORCID 0000-0002-7593-2385
Amar MiglaniDepartment of Otorhinolaryngology, Mayo Clinic in Arizona, Phoenix, Arizona, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSurgical repair and 3D-printed customized septal prosthesis (3D-PCSP) are options for septal perforation treatment. We performed a study to compare the clinical outcomes of surgery and 3D-PCSP using the NOSE-Perf Scale (NPfS).

methodsA chart review was performed on patients undergoing surgical repair or 3D-PCSP placement between January 2018 and July 2024. The change in NPfS was used as primary endpoint. Demographics, ASA score, perforation size, etiology, and follow-up duration were reported.

resultsThirty-five patients, 23 for surgical repairs and 12 for 3D-PCSP, were included in this review [median (IQR)]. In the surgical repair group, perforation length and height measured 12 (10-18) mm and 10 (8-15) mm, respectively. Baseline NPfS was 24 (16-32), and this decreased to 8 (6-13) following surgical repair (p < 0.001). Follow-up time was 12 (5-21) months. In the 3D-PCSP group, septal perforation length and height measured 25 (15-30) mm and 17 (15-20) mm, respectively. The baseline NPfS was 17 (3-24.5), and this decreased to 9.5 (7-13) following 3D-PCSP placement (p = 0.001). The follow-up was 18.4 (16-23) months. NPfS reduction was greater for surgical repair (p = 0.018).

conclusionsSurgery and 3D-PCSP offer meaningful symptom relief for NSP patients. Treatment decisions should be individualized through shared decision-making that considers patient comorbidities, preferences, surgeon experience, and risk tolerance. In this cohort, surgical repair was associated with greater NPfS reduction compared with 3D-PCSP placement. LEVEL OF EVIDENCE: 3:

Indexed as

Nasal Septal PerforationPrinting, Three-DimensionalProstheses and ImplantsProsthesis DesignAdultFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcome3D‐printed septal prosthesisnasal septal perforationNOSE‐Perf Scaleseptal buttonseptal perforation repair

Identifiers

PMID41844333
PMCPMC13357257

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.