ArticleJMIR research protocols2026
Evaluation of the Positive Peers Mobile App for Supporting the Viral Suppression of Young People With HIV: Protocol for a Concurrent Mixed Methods Evaluation With Randomized Controlled Clinical Trial and Observational Cohort.
Article in JMIR research protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06388109 (Randomized Control Trial of Positive Peers mHealth App as a Clinic-based Intervention to Optimize HIV Outcomes Among Young, Minority Persons Living With HIV), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Control Trial of Positive Peers mHealth App as a Clinic-based Intervention to Optimize HIV Outcomes Among Young, Minority Persons Living With HIV
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundPeople at greatest risk for poor HIV outcomes include young (13-34) people of color who have sex with men. Individuals in this population are least likely to be aware of their HIV status and are at the highest risk for disengaging from medical care and antiretroviral therapy. The Positive Peers mobile app (PPA) was designed to engage this population with real-time social support, HIV and healthy lifestyle information, and medical management tools. We expect that greater PPA engagement will predict key HIV care outcomes. Study predictions are grounded in a user-centric model of digital media use and the perceived affordances of the PPA.
objectiveThis study aims to determine the optimal deployment of the PPA in clinical settings (at enrollment vs delayed start) and to compare intervention outcomes with a no-intervention, observation-only condition. The PPA is designed specifically for key HIV disparity populations, including younger sexual, gender, racial, and ethnic minorities.
methodsThe Positive Peers Intervention Trial (PoPIT) is a multisite, randomized clinical trial designed to evaluate the effectiveness of the PPA as a tool for use in clinical settings. Trial arms compare the immediate deployment of the PPA with usual care and observation only. This protocol outlines a mixed methods design consisting of concurrent prospective self-report questionnaires, in-depth interviews with PPA users, and medical record review. PoPIT questionnaires include measures of social determinants of health, HIV-related stigma, perceptions of digital media use, self-efficacy, substance use, and social support. Multiple aspects of PPA intervention engagement are measured natively within the app. Outcomes include HIV National Quality Forum indicators and perceived HIV-related stigma.
resultsThe research protocol (1R01MD019185-01) was funded for US $903,363.00 in direct costs by the National Institute for Minority Health and Health Disparities on September 24, 2023, for 5 years. The study began recruiting patients on June 3, 2024, and will continue accrual until November 27, 2026.
conclusionsFindings will provide evidence of the usefulness of the PPA as a support tool in HIV clinical care. Primary results will inform optimization of PPA deployment and evaluate a theoretical model of user engagement with a mobile health management app. Qualitative data will provide a phenomenological description of intervention engagement and perceived user efficacy.
trial registrationClinicalTrials.gov NCT06388109; https://clinicaltrials.gov/ct2/show/NCT06388109. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/87601.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.