ArticleAnatolian journal of cardiology2026
The Postoperative Course of Troponin T and NT-proBNP Levels in the Pediatric Population Implanted with the HeartMate 3 Device.
Article in Anatolian journal of cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCardiac troponin T (cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are key biomarkers reflecting myocardial injury and hemodynamic load in heart failure or after cardiac surgery. However, data on their postoperative course in pediatric HeartMate 3 (HM3) recipients are limited. This retrospective case series of ten pediatric patients aimed to evaluate the clinical significance of postoperative changes in these biomarkers.
methodsThis retrospective case series included pediatric patients who underwent left ventricular assist device (LVAD) implantation between 2022 and 2024 at the center. Clinical and laboratory data were retrospectively obtained from medical records.
resultsTen patients with dilated cardiomyopathy (PEDIMACS profiles 1-3) were included. The median preoperative cTnT level was 98.5 [IQR 42.5-236.5] ng/L. Median postoperative cTnT levels were 182.6 [IQR 88.3-342.9] ng/L at 1 month, 54.0 [IQR 32.0-92.0] ng/L at 6 months, and 43.2 [IQR 25.8-71.4] ng/L at 12 months. Median B-type natriuretic peptide (BNP) levels were 7510 [IQR 5350-10850] ng/L preoperatively, 4122 [IQR 2963-7288] ng/L at 1 month, 853 [IQR 520.3-1426] ng/L at 6 months, and 1041 [IQR 619.8-1524] ng/L at 12 months. The mean intensive care unit (ICU) stay was 24.1 ± 16.3 days. Troponin levels returned to normal by postoperative month 6 in all but 2 patients. Spearman analysis showed a significant positive correlation between preoperative cTnT and ICU stay (ρ = 0.687, P = .028).
conclusionIn pediatric HM3 recipients, cTnT and NT-proBNP levels reflect postoperative myocardial recovery and may serve as clinically useful indicators associated with intensive care duration.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.