Evidence map›Paper›PMID 41843667›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Exploring the energy landscape of bacterial chromosome segregation.

Sumitabha Brahmachari, Antonio B Oliveira, Matheus F Mello, Vinícius G Contessoto, José N Onuchic

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Chromosome segregation in a minimal bacterial cell driven by SMC protein complexes.Protein science : a publication of the Protein Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sumitabha BrahmachariCenter for Theoretical Biological Physics, Rice University, Houston, TX 77005.ORCID 0000-0002-9091-6180
Antonio B OliveiraCenter for Theoretical Biological Physics, Rice University, Houston, TX 77005.
Matheus F MelloCenter for Theoretical Biological Physics, Rice University, Houston, TX 77005.
Vinícius G ContessotoCenter for Theoretical Biological Physics, Rice University, Houston, TX 77005.ORCID 0000-0002-1891-9563
José N OnuchicCenter for Theoretical Biological Physics, Rice University, Houston, TX 77005.ORCID 0000-0002-9448-0388

Funding

National Science Foundation (NSF) PHY-2014141National Science Foundation (NSF) PHY-2019745National Science Foundation (NSF) PHY-2210291Welch Foundation (The Welch Foundation) C-1792
6 · The paper itself

Abstract

Faithful chromosome segregation during bacterial replication requires global reorganization of the nucleoid, where Structural Maintenance of Chromosomes (SMC) complexes play a crucial role. Here, we develop an energy landscape framework that integrates data-driven pairwise interactions with coarse-grained polymer physics to infer the 3D architectural ensembles of

Indexed as

Bacillus subtilisChromosomes, BacterialEscherichia coliBacterial ProteinsDNA, BacterialEntropyReplication OriginThermodynamicsBacterial ProteinsDNA, Bacterialbacteria genomechromosome segregationenergy landscape dynamicsHi-C modelingSMC proteins

Identifiers

PMID41843667
PMCPMC13012044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.