ArticleScience signaling2026
The unphosphorylated, closed form of ezrin binds to RNA to maintain a metastatic phenotype in osteosarcoma cells.
Emre Deniz, Prakriti Tiwari, Purushottam B Tiwari, Eric Glasgow, Brent T Harris, Anup Tiwari, Chunyan Hou, Junfeng Ma, Jeffrey A Toretsky, Aykut Üren
Abstract read
In one paragraphArticle in Science signaling, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Emre DenizLombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.ORCID 0000-0002-9635-983X Prakriti TiwariLombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.
Purushottam B TiwariLombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.ORCID 0000-0002-3140-0723 Eric GlasgowLombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.ORCID 0000-0001-7729-3954 Brent T HarrisLombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.ORCID 0000-0002-9746-4906 Anup TiwariWalter Johnson High School, Bethesda, MD 20814, USA.
Chunyan HouLombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.ORCID 0000-0001-5966-1899 Junfeng MaLombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.ORCID 0000-0002-5183-5425 Jeffrey A ToretskyLombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.ORCID 0000-0003-3619-2879 Aykut ÜrenLombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.ORCID 0000-0002-2033-1216 Funding
NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6MCOG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8MTissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI MARCUS S NOEL · 1990 to 2026
$71.5MCOG U24 Funding 2026-2027U24CA196173 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI Mignon Lee-Cheun Loh, Nilsa Del Carmen Ramirez Milan · 2015 to 2026
$62.5MNCI NIH HHS P30 CA051008NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899NCI NIH HHS U24 CA196173
6 · The paper itselfAbstract
Ezrin is a cytoplasmic protein that can exist in multiple conformations that are regulated by phosphorylation at Thr
Indexed as
Bone NeoplasmsCytoskeletal ProteinsOsteosarcomaAnimalsCell Line, TumorEzrinHumansMiceNeoplasm MetastasisPhosphorylationProtein BindingRNA-Binding ProteinsZebrafishCytoskeletal ProteinsEzrinRNA-Binding Proteins
Identifiers
PMID41843652
PMCPMC13270438
What OpenQuestion holds
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