ReviewMusculoskeletal surgery2026
Systematic review of injections for acute ankle sprains.
Review in Musculoskeletal surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lateral ankle sprains are a common injury that can result in morbidity in terms of pain and time away from work or sport. Although it is typically self-resolving, treatments to expedite or enhance healing may be beneficial. One modality utilized by health care practitioners is the injection of therapeutic compounds. The purpose of this study is to determine the impact of injections of local anesthetics, platelet-rich plasma (PRP), and hyaluronic acid (HA) on patients with lateral ankle sprains. Systematic Review; Level of evidence 3. A comprehensive literature search was conducted in PubMed, Embase, Web of Science, Scopus, and the Cochrane Library on December 17th, 2024, by the Health Sciences Research Librarian. A total of 10 studies were included. 5 pertained to local anesthetic injections and demonstrated a favorable impact on recovery time. 3 manuscripts used PRP with 2 of the 3 finding improvements in the intervention group relative to the control up to 24 weeks from the injury. 2 manuscripts pertained to hyaluronic acid injections and one of the studies found relative improvements compared to the control in terms of pain control. Injections of PRP, hyaluronic acid, and local anesthetics may be able to improve recovery time and pain control for lateral ankle sprains; however, there remains a need for high-quality research to make recommendations for clinical practice.
Indexed as
Identifiers
41843366What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.