Evidence map›Paper›PMID 41843330›Full record

ArticleNeurosurgical review2026

Outcomes of orbital-cavernous sinus schwannomas via pterional approach combined with orbital osteotomy: a retrospective study of 32 cases.

Zhendan Zhu, Tengchao Huang, Xun Jiang, Zhenjun Li, Wenhan Zheng, Huasheng Yang, Ying Guo, Wensheng Li, Haiyong He

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Article in Neurosurgical review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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9 authors.

Zhendan Zhu *Department of Neurosurgery, Third Affiliated Hospital of Sun Yat-Sen University, 600 Tian he Road, Guangzhou, 510630, China.
Tengchao Huang *Department of Neurosurgery, Third Affiliated Hospital of Sun Yat-Sen University, 600 Tian he Road, Guangzhou, 510630, China.
Xun Jiang *Department of Neurosurgery, Third Affiliated Hospital of Sun Yat-Sen University, 600 Tian he Road, Guangzhou, 510630, China.
Zhenjun LiDepartment of Neurosurgery, Third Affiliated Hospital of Sun Yat-Sen University, 600 Tian he Road, Guangzhou, 510630, China.
Wenhan ZhengDepartment of Neurosurgery, Third Affiliated Hospital of Sun Yat-Sen University, 600 Tian he Road, Guangzhou, 510630, China.
Huasheng YangDepartment of Eye Tumor and Orbital Disease, Zhongshan Ophthalmic Center (ZOC) of Sun Yat-Sen University, Guangzhou, China.
Ying GuoDepartment of Neurosurgery, Third Affiliated Hospital of Sun Yat-Sen University, 600 Tian he Road, Guangzhou, 510630, China.
Wensheng LiDepartment of Neurosurgery, Third Affiliated Hospital of Sun Yat-Sen University, 600 Tian he Road, Guangzhou, 510630, China.
Haiyong HeDepartment of Neurosurgery, Third Affiliated Hospital of Sun Yat-Sen University, 600 Tian he Road, Guangzhou, 510630, China. jlhhy007@126.com.

Funding

the basic and applied basic research foundation of Guangdong Province 2022A1515012233the R & D program of key fields in Guangdong Province 2020b090924004
6 · The paper itself

Abstract

objectiveSurgical outcomes for the orbital-cavernous sinus schwannomas are limited. Therefore, the current study aims to present and evaluated surgical strategies and clinical outcomes in orbital-cavernous sinus schwannomas in our center.

methodsA retrospective analysis was conducted in patients with orbital-cavernous sinus schwannomas who underwent surgery via the pterional approach combined with orbital osteotomy at our center between January 2016 and December 2024. Clinical data, extent of resection, postoperative neurological function and surgical complications were evaluated.

resultsA total of 32 patients were included in the current study. Gross total resection was achieved in 28 cases (87.50%) and subtotal resection was achieved in 4 cases (12.50%). After surgery, visual acuity was improved in 6 patients (18.75%), remained unchanged in 24 patients (75.00%), and worsened in 2 patients (6.25%). Proptosis improved in 32 patients (100%). Ptosis occurred in 11 patients, with 9 patients fully recovered during the follow-up and the remaining 2 patients experienced partial recovery. 2 patients experienced impaired ocular abduction, and were recovered within 3 months post-surgery.

conclusionSurgical intervention plays an important role in the treatment of orbital-cavernous sinus schwannomas. The pterional approach combined with orbital osteotomy achieved high resection rate, symptom relief, and a low incidence of complications.

Indexed as

Cavernous SinusCavernous Sinus SyndromesNeurilemmomaNeurosurgical ProceduresOrbitOrbital NeoplasmsOsteotomyAdolescentAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcomecavernous sinusorbitalproptosisschwannomavisual acuity

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.