ReviewVeterinary research communications2026
General anesthesia and depth of anesthesia (DoA) evaluation methods in laboratory animals: a comprehensive review.
Review in Veterinary research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- A reporting checklist for human and animal heart rate variability research.Pflugers Archiv : European journal of physiology · 2026Review
- Development and Optimization of Sorafenib Nanosuspension By High-pressure Homogenization for Improved Oral Bioavailability.Pharmaceutical research · 2026Article
- Flecainide- and isoproterenol-induced alterations in heart rate variability and DFA-derived physiological complexity in anesthetized mice.BMC cardiovascular disorders · 2026Article
- The Impact of Etomidate on Tear Secretion and Oxidative Stress Markers in Domestic Male Cats: A Clinical Study.Veterinary medicine international · 2026Article
- Comparative analysis of anesthetic protocols in spontaneously hypertensive rats with sepsis-induced hemodynamic instability.Frontiers in veterinary science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In preclinical research, general anesthesia is essential for humane and feasible procedures but profoundly modulates autonomic, cardiovascular, neurological, and biochemical systems, risking bias in experimental outcomes. In this review our aim was to synthesize current knowledge on commonly used general anesthetics in laboratory animals, their mechanisms and protocols across species (mice, rats, rabbits, pigs), and evidence-based methods to evaluate depth of anesthesia (DoA). Injectable agents (ketamine with α
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.