Evidence map›Paper›PMID 41843028›Full record

ArticleActa neurologica Belgica2026

A novel application of the lorenz plot method for ultra-short-term evaluation of autonomic nervous function.

Sakura Tatsumi, Daisuke Kuratsune, Hirohiko Kuratsune

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Article in Acta neurologica Belgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Sakura TatsumiDivision of Health Sciences, Osaka University Graduate School of Medicine, 1-7 Yamadaoka, Suita, 565-0871, Osaka, Japan. sakura@fmcc.co.jp.ORCID http://orcid.org/0000-0002-6280-056X
Daisuke KuratsuneFatigue Science Laboratory Inc, 7-4-21 Nishinakajima, Yodogawa-ku, Osaka, 532- 0011, Japan.
Hirohiko KuratsuneDivision of Health Sciences, Osaka University Graduate School of Medicine, 1-7 Yamadaoka, Suita, 565-0871, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeart rate variability (HRV) analysis is widely used to assess autonomic nervous function (ANF); however, conventional frequency-domain indices require recording durations that may limit their applicability in settings requiring rapid or repeated measurements. This study investigated whether measurement duration could be reduced by estimating high-frequency power (HF), an index of parasympathetic modulation, from ultra-short-term (UST) recording windows using a Lorenz plot (LP)-based estimation model.

methodsElectrocardiographic data were recorded during a 2-min resting, eyes-closed condition. HF was calculated exclusively from the full 120-s recording using frequency-domain analysis and served as the reference outcome. LP indices were computed from progressively shorter R-R interval (RRI) windows (120-5 s) and, together with age, were used to construct regression models to estimate the 120-s HF reference value. No frequency-domain analysis was performed on the shortened windows.

resultsThe LP-based estimation model demonstrated robust performance across window lengths. Even when LP indices were computed from as little as 5 s of data, the model retained acceptable predictive accuracy for estimating the HF reference value derived from the 120-s recording (adjusted R

conclusionsParasympathetic modulation reflected in conventional 120-s frequency-domain HF analysis can be estimated with practical accuracy from UST recordings as short as 5 s using the LP-based estimation model. The proposed model does not confer interchangeability with standard frequency-domain HF indices across time scales. Rather, it offers a practical marker for rapid estimation of the 120-s frequency-domain HF reference value when longer recordings are impractical.

Indexed as

Autonomic Nervous SystemElectrocardiographyHeart RateFemaleHumansMaleTime FactorsAutonomic nervous function (ANF)High-frequency power (HF)Shortened evaluationThe Lorenz plot (LP) method

Identifiers

PMID41843028

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.