Evidence map›Paper›PMID 41843011›Full record

ArticleAmerican journal of clinical dermatology2026

Factors Associated with Symptomatic Dermographism: Findings from the UCARE PREVALENCE-D Study.

Kanokvalai Kulthanan, Jonathan A Bernstein, Michael Rudenko, Pascale Salameh, Chulaluk Komoltri, Zainab Abdul Hameed, Esra Adışen, Salma Al Abri, Mona Al-Ahmad, Bushra Al Hinai and 52 more

Abstract readMulticenter Study
In one paragraph

Article in American journal of clinical dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

62 authors.

Kanokvalai KulthananDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-7618-821X
Jonathan A BernsteinDivision of Rheumatology, Allergy and Immunology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.ORCID https://orcid.org/0000-0002-3476-1196
Michael RudenkoLondon Allergy and Immunology Centre, London, UK.ORCID https://orcid.org/0000-0002-6065-9451
Pascale SalamehInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-4780-0772
Chulaluk KomoltriDivision of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0001-8620-1126
Zainab Abdul HameedClinical Immunology and Allergy Unit, Royal Hospital, Muscat, Oman.ORCID https://orcid.org/0000-0003-4299-2979
Esra AdışenDepartment of Dermatology, Faculty of Medicine, Gazi University, Ankara, Türkiye.ORCID https://orcid.org/0000-0002-8768-231X
Salma Al AbriClinical Immunology and Allergy Unit, Royal Hospital, Muscat, Oman.ORCID https://orcid.org/0000-0002-8454-0383
Mona Al-AhmadCollege of Medicine, Kuwait University, Kuwait City, Kuwait.ORCID https://orcid.org/0000-0003-2950-5363
Bushra Al HinaiClinical Immunology and Allergy Unit, Royal Hospital, Muscat, Oman.ORCID https://orcid.org/0000-0002-3266-7091
Anastasiia AllenovaLaboratory of Immune-mediated Skin Diseases, Institute of Regenerative Medicine, Biomedical Science & Technology Park, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation.ORCID https://orcid.org/0000-0003-0751-0073
Saad AlshareefKing Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0001-8308-4374
Nattha AngkoolpakdeekulDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-6388-1939
Rand ArnaoutKing Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0003-3951-5880
Joanna BartosińskaDepartment of Cosmetology and Aesthetic Medicine, Medical University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0003-4106-3051
Ivan Cherrez-OjedaInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-1610-239X
Leena ChularojanamontriDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0001-6625-6445
Paulo Ricardo CriadoDepartment of Dermatology, Centro Universitário Faculdade de Medicina do ABC, Santo André, Brazil.ORCID https://orcid.org/0000-0001-9785-6099
Heyam ElsaeedAl-Rashed Allergy Center, Ministry of Health, Kuwait City, Kuwait.ORCID https://orcid.org/0009-0004-1975-1944
Roberta Fachini Jardim CriadoDepartment of Dermatology, Centro Universitário Faculdade de Medicina do ABC, Santo André, Brazil.ORCID https://orcid.org/0000-0003-2482-3047
Ahmed FarahatAl-Rashed Allergy Center, Ministry of Health, Kuwait City, Kuwait.ORCID https://orcid.org/0009-0009-7370-5291
Cesar Alberto Galvan CalleEmedic Salud, Lima, Peru.ORCID https://orcid.org/0000-0003-3517-3051
Ana Maria Giménez-ArnauDepartment of Dermatology, Hospital del Mar Research Institute, Universitat Pompeu Fabra, Barcelona, Spain.ORCID https://orcid.org/0000-0001-5434-7753
Kiran GodseDepartment of Dermatology, D. Y. Patil University and School of Medicine, Navi Mumbai, India.ORCID https://orcid.org/0000-0002-0550-5871
Maia GotuaCenter of Allergy and Immunology, David Tvildiani Medical University, Tbilisi, Georgia.ORCID https://orcid.org/0000-0003-2497-4128
Mehmet GülengülDepartment of Dermatology, Faculty of Medicine, Gazi University, Ankara, Türkiye.ORCID https://orcid.org/0000-0002-8017-5729
Michihiro HideDepartment of Dermatology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.ORCID https://orcid.org/0000-0002-1569-6034
Naoko InomataDepartment of Dermatology, Showa University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-1989-9824
Chang-Gyu JungDepartment of Allergy and Clinical Immunology, Keimyung University School of Medicine, Daegu, South Korea.ORCID https://orcid.org/0000-0001-9163-9253
Alicja Kasperska-ZającDepartment of Clinical Allergology and Urticaria, Medical University of Silesia, Silesia, Poland.ORCID https://orcid.org/0000-0002-2000-0070
Maryam KhoshkhuiAllergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0000-0002-0363-6536
Pavel KolkhirInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0001-5380-8132
Dorota KrasowskaDepartment of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0002-3176-9870
Jomgriditip LaomoleethornDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0005-0834-2229
Antonina MaiorowaSmolensk State Medical University, Smolensk, Russia.ORCID https://orcid.org/0009-0002-3810-2734
Prynn ManuskiattiDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0007-4734-4790
Raisa MeshkovaSmolensk State Medical University, Smolensk, Russia.ORCID https://orcid.org/0000-0002-7806-9484
Dragan MijakoskiInstitute of Occupational Health of R.N. Macedonia, WHO Collaborating Center, GA2LEN Collaborating Center, Skopje, Republic of North Macedonia.ORCID https://orcid.org/0000-0002-3291-0661
Melba MuñozInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0003-3386-4502
Iman NasrClinical Immunology and Allergy Unit, Royal Hospital, Muscat, Oman.ORCID https://orcid.org/0000-0003-0346-9675
Denise Neiva Santos de Aquino ArnoldiDivision of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Urticaria Center of Reference and Excellence (UCARE), Federal University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-4065-4071
Rabia Öztaş KaraDepartment of Dermatology, Faculty of Medicine, Sakarya University, Sakarya, Türkiye.ORCID https://orcid.org/0000-0003-1828-5844
Teerapat ParingkarnDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0008-5067-9759
Juliette Pérez-ManichDepartment of Dermatology, Hospital de Viladecans, Barcelona, Spain.ORCID https://orcid.org/0000-0003-2900-1173
Indrashis PodderDepartment of Dermatology, College of Medicine and Sagore Dutta Hospital, Kolkata, India.ORCID https://orcid.org/0000-0002-9589-083X
Karla Robles-VelascoUniversidad Espíritu Santo, Samborondón, Ecuador.ORCID https://orcid.org/0000-0001-7780-1015
Isabel RosmaninhoUnidade Local de Saúde Gaia e Espinho, Vila Nova de Gaia, Portugal.ORCID https://orcid.org/0009-0005-0377-6554
Phuwakorn Saengthong-AramDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0005-1730-788X
Giorgi ShengelidzeCenter of Allergy and Immunology, David Tvildiani Medical University, Tbilisi, Georgia.ORCID https://orcid.org/0009-0000-6469-8194
Sariya SittiwanarukDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0005-5236-4193
Rana TafrishiAllergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0009-0004-6564-8737
Natasa Teovska MitrevskaDermatology Department, Remedika General Hospital, Skopje, Republic of North Macedonia.ORCID https://orcid.org/0000-0003-2009-3833
Vesna TrajkovaGeneral Hospital "8th September", Skopje, Republic of North Macedonia.ORCID https://orcid.org/0009-0000-4043-2236
Papapit TuchindaDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-0599-4062
Noldtawat ViriyaskultornDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0008-8881-6456
Teerapat WannawittayapaDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0008-3500-1018
Pornjira WattanasillawatDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0008-0100-8326
Anushka WilsonDepartment of Dermatology, D. Y. Patil University and School of Medicine, Navi Mumbai, India.ORCID https://orcid.org/0009-0005-5946-359X
Young-Min YeDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.ORCID https://orcid.org/0000-0002-7517-1715
Anna Zalewska-JanowskaPsychodermatology Department, Medical University of Lodz, Lodz, Poland.ORCID https://orcid.org/0000-0001-9900-7680
Marcus MaurerInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-4121-481X
Torsten ZuberbierInstitute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. torsten.zuberbier@charite.de.ORCID http://orcid.org/0000-0002-1466-8875

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveSymptomatic dermographism (SD), the most common chronic inducible urticaria subtype, manifests as strip-shaped, pruritic wheals after skin friction. Conclusive data on its associated factors are limited, and direct comparisons between individuals with and without SD remain scarce. We aimed to identify factors associated with SD internationally.

methodsThe PREVALENCE-D (Prevalence Estimation of Dermographism) study was an international cross-sectional survey conducted from 2021 to 2024 across 19 countries. An expert-designed questionnaire diagnosed SD and assessed potential associated factors. SD participants were defined as those who self-reported chronic recurrent urticarial dermographism with itch. Factors associated with SD were identified by comparing participants with and without SD.

resultsOf 68,513 participants, 3101 had SD (female 73.3%). Their mean age was 40.2 ± 16.2 years. Key factors associated with SD included atopic dermatitis (adjusted odds ratio [aOR] 4.20, 95% confidence interval [CI] 3.62‒4.88) and allergic rhinitis (aOR 2.11, 95% CI 1.88‒2.37). Participants with at least one atopic condition (allergic rhinitis, atopic dermatitis, or asthma) were significantly more likely to have SD (aOR 2.70, 95% CI 2.47‒2.95). Those with all three atopic conditions had a further increased likelihood of SD (aOR 7.75, 95% CI 5.31‒11.29). Other associations included working and older age groups, female sex, dyslipidemia, and thyroid disease.

conclusionsAtopic dermatitis and allergic rhinitis emerged as the strongest correlates of SD, especially those with all three atopic conditions. Thus, allergic comorbidities should be assessed in SD patients. Further research is needed to clarify the pathophysiological relationship between these conditions and SD. [Graphical abstract available online].

Indexed as

Chronic UrticariaDermatitis, AtopicPruritusRhinitis, AllergicUrticariaAdultChronic Inducible UrticariaCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsYoung Adult

Identifiers

PMID41843011
PMCPMC13171654

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