ArticleMicrobiology spectrum2026
Targeting MCR-3 and membrane biosynthesis: mechanistic insights into pterostilbene-colistin synergy.
Fei Zeng, Wenjuan Yin, Huilian Duan, Shuxin He, Luying Sun, Jie Zhang, Siming Wang, Feng Liu, Yuangong Zhang
Abstract read
In one paragraphArticle in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
9 authors.
Fei ZengKey Laboratory of Pathogenesis Mechanism and Control of Inflammatory Autoimmune Disease of Hebei Province, School of Basic Medicine Science, Hebei University, Baoding, China.
Wenjuan YinKey Laboratory of Pathogenesis Mechanism and Control of Inflammatory Autoimmune Disease of Hebei Province, School of Basic Medicine Science, Hebei University, Baoding, China.ORCID 0009-0009-9695-8224 Huilian DuanKey Laboratory of Pathogenesis Mechanism and Control of Inflammatory Autoimmune Disease of Hebei Province, School of Basic Medicine Science, Hebei University, Baoding, China.
Shuxin HeKey Laboratory of Pathogenesis Mechanism and Control of Inflammatory Autoimmune Disease of Hebei Province, School of Basic Medicine Science, Hebei University, Baoding, China.
Luying SunKey Laboratory of Pathogenesis Mechanism and Control of Inflammatory Autoimmune Disease of Hebei Province, School of Basic Medicine Science, Hebei University, Baoding, China.
Jie ZhangKey Laboratory of Pathogenesis Mechanism and Control of Inflammatory Autoimmune Disease of Hebei Province, School of Basic Medicine Science, Hebei University, Baoding, China.
Siming WangKey Laboratory of Pathogenesis Mechanism and Control of Inflammatory Autoimmune Disease of Hebei Province, School of Basic Medicine Science, Hebei University, Baoding, China.
Feng LiuKey Laboratory of Pathogenesis Mechanism and Control of Inflammatory Autoimmune Disease of Hebei Province, School of Basic Medicine Science, Hebei University, Baoding, China.ORCID 0000-0001-9815-4187 Yuangong ZhangKey Laboratory of Pathogenesis Mechanism and Control of Inflammatory Autoimmune Disease of Hebei Province, School of Basic Medicine Science, Hebei University, Baoding, China.ORCID 0000-0001-5264-560X Funding
National Natural Science Foundation of China 82471463Natural Science Foundation of Hebei Province H2024201044The Central Guidance on Local Science and Technology Development Fund of Hebei Province 226Z2604GThe Medical Scientific Research of Hebei Health Commission 20231560
6 · The paper itselfAbstract
Colistin is a crucial antibiotic for treating infections caused by multidrug-resistant Enterobacterales. However, the emergence of plasmid-mediated
Indexed as
Anti-Bacterial AgentsColistinEscherichia coliEscherichia coli ProteinsStilbenesAnimalsCell MembraneDrug SynergismEscherichia coli InfectionsEthanolaminephosphotransferaseMicrobial Sensitivity TestsMolecular Docking SimulationTransferases (Other Substituted Phosphate Groups)Anti-Bacterial AgentsColistinEscherichia coli ProteinsEthanolaminephosphotransferaseMCR-3 protein, E colipterostilbeneStilbenesTransferases (Other Substituted Phosphate Groups)antibiotic adjuvantcolistinMCR-3membrane disruptionpterostilbene
Identifiers
PMID41841732
PMCPMC13055306
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