Evidence map›Paper›PMID 41841662›Full record

ArticleOphthalmic epidemiology2026

Associations Between Social Determinants of Health and Treatment of Exudative Age-Related Macular Degeneration: A Retrospective Cohort Analysis.

Timothy M Janetos, Manjot K Gill, Dustin D French

Abstract read
In one paragraph

Article in Ophthalmic epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Timothy M JanetosDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Manjot K GillDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Dustin D FrenchDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

Funding

NUCATS CTSA K12 Program at Northwestern UniversityK12TR005104 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Leena Sharma, BETINA YANEZ · 2024 to 2026
$3.2M
NCATS NIH HHS K12 TR005104
6 · The paper itself

Abstract

purposeTo evaluate associations between social determinants of health (SDOH) and treatment rates among patients with exudative age-related macular degeneration (exAMD).

methodsRetrospective cohort study of patients with exAMD utilizing data from the NIH

resultsAmong sociodemographic factors, Black individuals had significantly lower injection rates (IRR: 0.32, 95% CI: 0.13-0.79) compared to White individuals. When correcting for multiple comparisons, among the SDOH constructs, there were none that were significantly associated with treatment rate. Within the exploratory factor analysis, a factor identified by poor English proficiency, transportation difficulty, rural care access issues, worse health literacy, and provider concordance issues was associated with a significantly decreased rate of treatment (IRR: 0.73, 95% CI: 0.55-0.96), as well as a factor identified by high neighborhood disorder, high loneliness, high perceived health care and everyday discrimination, and high stress (IRR: 0.74, 95% CI: 0.60-0.92).

conclusionsThis study identifies significant racial disparities and SDOH constructs associated with exAMD treatment rates. These findings underscore the complexity of sociodemographic influences on treatment and suggest potential inequities which warrant additional study.

Indexed as

Angiogenesis InhibitorsSocial Determinants of HealthWet Macular DegenerationAgedAged, 80 and overFemaleHumansIntravitreal InjectionsMaleRanibizumabRetrospective StudiesSocioeconomic Disparities in HealthUnited StatesAngiogenesis InhibitorsRanibizumabExudative macular degenerationhealth equityintravitreal injectionssocial determinants of healthtreatment

Identifiers

PMID41841662
PMCPMC13019831

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.