Evidence map›Paper›PMID 41841459›Full record

ArticleFoot & ankle international2026

Peroneal Artery Danger Zone With Syndesmotic Screw Fixation: A Computed Tomography Angiography Study.

Garrett K Berger, Avinaash Korrapati, Aaron Tran, Zachary Brumm, Sean Thomas, Kevin Y Zhu, William T Kent

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Article in Foot & ankle international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Garrett K BergerDepartment of Orthopaedic Surgery, University of California-San Diego, San Diego, CA, USA.
Avinaash KorrapatiDepartment of Orthopaedic Surgery, University of California-San Diego, San Diego, CA, USA.
Aaron TranDepartment of Orthopaedic Surgery, University of California-San Diego, San Diego, CA, USA.
Zachary BrummSchool of Medicine, University of California-San Francisco, San Francisco, CA, USA.
Sean ThomasDepartment of Orthopaedic Surgery, University of California-San Diego, San Diego, CA, USA.
Kevin Y ZhuDepartment of Orthopaedic Surgery, University of California-San Diego, San Diego, CA, USA.ORCID 0000-0003-0521-0819
William T KentDepartment of Orthopaedic Surgery, University of California-San Diego, San Diego, CA, USA.ORCID 0000-0002-7065-9551

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdditional trans-syndesmotic screws (TSS) are used in "fibula pro-tibia" approach for unstable ankle fractures applied to high-risk patients (diabetes, smoking, osteoporosis, obesity). These patients are at higher risk of complications. The peroneal artery (PA) may be at risk with additional TSS fixation. Iatrogenic vascular compromise may explain these postoperative complications. Therefore, this study investigates the range in which the PA and its deep perforating branch (dPA) are at risk with TSS fixation and identifies safe zones to avoid iatrogenic injury in this vulnerable population.

methodsA retrospective analysis of lower extremity computed tomography angiograms (CTAs) was performed (2021-2022) in specified patients with comorbidities who might benefit from multiple syndesmotic screw fixation. CTAs were reformatted in the syndesmotic plane, and the PA was deemed at risk if a templated 3.5-mm syndesmotic screw intersected its course. Measurements were taken from both the tibial plafond and fibular tip and included the level where the PA and dPA branch entered and exited this danger zone.

resultsNinety-eight CTAs (196 limbs) were analyzed. Seventy-two patients were age ≥ 65 (mean 75, SD 8), 52 had diabetes, 16 were active nicotine users, and 16 had BMI ≥35. The PA was at risk in 98.5% (n = 195) limbs. The danger zone began 7.5 cm (SD 1.5 cm) proximal to the tibial plafond and 10 cm (SD 1.5 cm) proximal to the fibular tip. The dPA branch perforated the syndesmotic plane at 3.6 cm (SD 0.8 cm) proximal from the plafond and 6 cm (SD 0.9 cm) from the fibular tip. Finally, the PA and dPA were out of the danger zone at 2.5 cm (SD 0.4 cm) proximal from the tibial plafond and 5 cm (SD 0.6 cm) from the fibular tip. No difference was found between inclusion subgroups nor between individual patients' contralateral legs.

conclusionPA and dPA are at risk with TSS, notably in the distal fifth of the limb, ending ~2.5 cm proximal to the plafond. Knowledge of this zone aids in planning for TSS fixation, especially for high-risk patients.

Indexed as

Ankle FracturesBone ScrewsComputed Tomography AngiographyFracture Fixation, InternalAgedFemaleHumansMaleRetrospective Studiesperoneal arterysyndesmosissyndesmotic screwunstable anklevascular injury

Identifiers

PMID41841459
PMCPMC13168621

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.