Evidence map›Paper›PMID 41841247›Full record

ArticleHypertension (Dallas, Tex. : 1979)2026

Hypertensive Disorders of Pregnancy and Primary Aldosteronism.

Stéfanie Parisien-La Salle, Arnaldo Ferrebus, Eva E Abel, Laura C Tsai, Andrew J Newman, Cheng-Hsuan Tsai, Anand Vaidya, Jenifer M Brown

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Stéfanie Parisien-La SalleDivision of Endocrinology, Diabetes, and Hypertension, Center for Adrenal Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.P.-L.S., A.F., E.E.A., L.C.T., A.J.N., C-H.T., A.V., J.M.B.).ORCID 0000-0001-5960-4181
Arnaldo FerrebusDivision of Endocrinology, Diabetes, and Hypertension, Center for Adrenal Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.P.-L.S., A.F., E.E.A., L.C.T., A.J.N., C-H.T., A.V., J.M.B.).ORCID 0009-0009-0558-2154
Eva E AbelDivision of Endocrinology, Diabetes, and Hypertension, Center for Adrenal Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.P.-L.S., A.F., E.E.A., L.C.T., A.J.N., C-H.T., A.V., J.M.B.).
Laura C TsaiDivision of Endocrinology, Diabetes, and Hypertension, Center for Adrenal Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.P.-L.S., A.F., E.E.A., L.C.T., A.J.N., C-H.T., A.V., J.M.B.).ORCID 0009-0008-5344-2589
Andrew J NewmanDivision of Endocrinology, Diabetes, and Hypertension, Center for Adrenal Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.P.-L.S., A.F., E.E.A., L.C.T., A.J.N., C-H.T., A.V., J.M.B.).ORCID 0000-0002-8326-1964
Cheng-Hsuan TsaiDivision of Endocrinology, Diabetes, and Hypertension, Center for Adrenal Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.P.-L.S., A.F., E.E.A., L.C.T., A.J.N., C-H.T., A.V., J.M.B.).ORCID 0000-0003-2859-5117
Anand VaidyaDivision of Endocrinology, Diabetes, and Hypertension, Center for Adrenal Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.P.-L.S., A.F., E.E.A., L.C.T., A.J.N., C-H.T., A.V., J.M.B.).ORCID 0000-0002-0314-9252
Jenifer M BrownDivision of Endocrinology, Diabetes, and Hypertension, Center for Adrenal Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.P.-L.S., A.F., E.E.A., L.C.T., A.J.N., C-H.T., A.V., J.M.B.).ORCID 0000-0002-6647-639X

Funding

Unrecognized Primary Aldosteronism as a Pathogenic Mechanism for Chronic Kidney Disease in DiabetesR01DK115392 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI Anand Vaidya · 2018 to 2026
$6.0M
Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in ObesityR01HL153004 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI VAIDYA, ANAND · 2020 to 2024
$4.4M
Cardiac Perfusion, Structure, and Function across the Primary Aldosteronism SpectrumK23HL159279 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Jenifer Michelle Brown · 2022 to 2026
$1.0M
NHLBI NIH HHS K23 HL159279NHLBI NIH HHS R01 HL153004NIDDK NIH HHS R01 DK115392
6 · The paper itself

Abstract

backgroundHypertensive disorders of pregnancy (HDP) affect up to 15% of pregnancies and are linked to adverse maternal and fetal outcomes. Primary aldosteronism (PA) affects up to 25% of patients with hypertension. In women with prior HDP and PA risk factors, we examined PA prevalence and its relationship to hypertension trajectory.

methodsAdults across the US meeting guideline-recommended screening criteria for PA were prospectively tested. Women with a self-reported history of HDP completed a questionnaire examining the relationship between PA and hypertension trajectory.

resultsOf 330 hypertensive parous women (62.4±9.8 years; 32.1% non-White), 83 (25.2%) reported a history of HDP. Women with HDP were younger at hypertension diagnosis (38.8 versus 47.9 years;

conclusionsOver 25% of women with hypertension, ≥1 PA risk factor, and prior pregnancy tested positive for PA, highlighting its high prevalence, irrespective of a history of HDP. Women with HDP face elevated cardiovascular risk, and PA may represent a targetable contributor.

Indexed as

HyperaldosteronismHypertension, Pregnancy-InducedAdultFemaleHumansMiddle AgedPregnancyPrevalenceProspective StudiesRisk FactorsSurveys and QuestionnairesUnited Statesaldosteronealdosteronismgestational hypertensionhypertensionpre-eclampsia

Identifiers

PMID41841247
PMCPMC13002124

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.