Evidence map›Paper›PMID 41841212›Full record

ArticleInorganic chemistry2026

Challenging the Macrocycle Paradigm: Four-Arm, High-Denticity Acyclic Chelators for Radiopharmaceuticals Incorporating Actinium and Lanthanides.

Daniel Fernández-Pavón, Andrés de Blas, María Martínez-Cabanas, José L Barriada, Brian O Patrick, Chris Orvig, François Bénard, Hua Yang, Luke Wharton, María de Guadalupe Jaraquemada-Peláez and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Inorganic chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daniel Fernández-PavónGrupo METMED, Departamento de Química, Universidade da Coruña, Campus da Zapateira s/n, 15071A Coruña, Spain.
Andrés de BlasGrupo METMED, Departamento de Química, Universidade da Coruña, Campus da Zapateira s/n, 15071A Coruña, Spain.ORCID 0000-0001-8548-9658
María Martínez-CabanasGrupo METMED, Departamento de Química, Universidade da Coruña, Campus da Zapateira s/n, 15071A Coruña, Spain.ORCID 0000-0002-6077-7474
José L BarriadaGrupo METMED, Departamento de Química, Universidade da Coruña, Campus da Zapateira s/n, 15071A Coruña, Spain.
Brian O PatrickDepartment of Chemistry, University of British Columbia, Vancouver, BC V6T 1Z1, Canada.ORCID 0000-0002-2921-8439
Chris OrvigMedicinal Inorganic Chemistry Group, Department of Chemistry, University of British Columbia, Vancouver, BC V6T 1Z1, Canada.ORCID 0000-0002-2830-5493
François BénardDepartment of Molecular Oncology, BC Cancer Research Institute, Vancouver, BC V5Z 1L3, Canada.ORCID 0000-0001-7995-3581
Hua YangLife Sciences Division, TRIUMF, 4004 Wesbrook Mall, Vancouver, BC V6T 2A3, Canada.ORCID 0000-0003-1833-9515
Luke WhartonLife Sciences Division, TRIUMF, 4004 Wesbrook Mall, Vancouver, BC V6T 2A3, Canada.ORCID 0000-0002-0636-8741
María de Guadalupe Jaraquemada-PeláezDepartment of Molecular Oncology, BC Cancer Research Institute, Vancouver, BC V5Z 1L3, Canada.
Teresa Rodríguez-BlasGrupo METMED, Departamento de Química, Universidade da Coruña, Campus da Zapateira s/n, 15071A Coruña, Spain.ORCID 0000-0001-5078-1093

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an alternative to macrocyclic chelators, a family of high-denticity, acyclic chelating agents based on picolinate arms has been devised with the aim of finding versatile chelating agents for

Indexed as

ActiniumChelating AgentsCoordination ComplexesLanthanoid Series ElementsMacrocyclic CompoundsRadiopharmaceuticalsHumansLigandsMolecular StructureActiniumChelating AgentsCoordination ComplexesLanthanoid Series ElementsLigandsMacrocyclic CompoundsRadiopharmaceuticals

Identifiers

PMID41841212
PMCPMC13040536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.