Evidence map›Paper›PMID 41841116›Full record

ArticleDiscover public health2026

Elevated prevalence of age-related macular degeneration in a low-income urban primary care setting.

Adriana Kaganovski, Alauddin Bhuiyan, Anisha Kasi, Daniel Kamyab, Aliya Grinberg, Sophie Chen, Robert Thomson, Tasin Bhuiyan, Arun Govindaiah, Avnish Deobhakta and 5 more

Abstract read
In one paragraph

Article in Discover public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Adriana KaganovskiDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 E 14th St, NY New York, 10003-4201 USA.
Alauddin BhuiyaniHealthScreen Inc, New York, NY USA.
Anisha KasiDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 E 14th St, NY New York, 10003-4201 USA.
Daniel KamyabSUNY Downstate Health Sciences University, New York, NY USA.
Aliya GrinbergSchool of Science, The College of New Jersey, Ewing, NJ USA.
Sophie ChenDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 E 14th St, NY New York, 10003-4201 USA.
Robert ThomsonMcGovern Medical School at The University of Texas Health Science Center, Houston, TX USA.
Tasin BhuiyaniHealthScreen Inc, New York, NY USA.
Arun GovindaiahiHealthScreen Inc, New York, NY USA.
Avnish DeobhaktaDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 E 14th St, NY New York, 10003-4201 USA.
Gareth LemaDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 E 14th St, NY New York, 10003-4201 USA.
Katy TaiDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 E 14th St, NY New York, 10003-4201 USA.
Matthew A WeissmanIcahn School of Medicine at Mount Sinai, New York, NY USA.
Leonard AmorusoIcahn School of Medicine at Mount Sinai, New York, NY USA.
R Theodore SmithDepartment of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 E 14th St, NY New York, 10003-4201 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Age-related macular degeneration (AMD) is the leading cause of vision loss among adults over 50. Early detection enables interventions such as Age-Related Eye Disease Study (AREDS) supplementation to slow disease progression, yet AMD remains underdiagnosed in primary care, particularly in underserved populations. This study assessed AMD sample prevalence and its association with social determinants of health in a diverse, urban primary care cohort. Methods: We performed a post hoc analysis of a cross-sectional study conducted from June 2020 to May 2023 at a hospital-based primary care clinic in New York City (NYC). Patients aged 50-89 underwent nonmydriatic color fundus photography graded independently by two physicians using Beckman Initiative criteria. Median household income by ZIP code served as a proxy for socioeconomic position. Multivariable logistic regression examined associations between AMD and demographic or social determinants of health variables. Results: Of 393 patients enrolled, 312 were included in the final analysis. Referable AMD was present in 48.4% of participants based on the Beckman classification, representing the sample prevalence within this clinic cohort and exceeding national population-based estimates. Only 4 of 151 AMD cases had been previously diagnosed. Referable AMD prevalence was higher in males than females (56.2% vs. 44.4%) and increased with age. Median household income was significantly lower among patients with referable AMD compared with those without ($72,000 vs. $151,000; Conclusion: Undiagnosed referable AMD was highly prevalent within this primary care clinic sample of low-income, urban patients. Integrating affordable retinal screening, potentially aided by artificial intelligence, into primary care may help address vision health disparities driven by social determinants of health. Supplementary Information: The online version contains supplementary material available at 10.1186/s12982-026-01672-0.

Identifiers

PMID41841116
PMCPMC12989009

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.