Evidence map›Paper›PMID 41841056›Full record

ArticleCureus2026

Multibacillary Leprosy With Accelerated Progression: A Case Report of an Atypical Clinical Presentation and Therapeutic Approach.

Carmen Reyes Reyna, David Fernando Narvaez-De Los Rios, Daniel Ibanez Vasquez, Sofia Simaluisa, Anabel Huaman Boza, Alison Cristina Jimenez Ordoñez

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carmen Reyes ReynaInternal Medicine, Universidad Nacional Mayor De San Marcos, Lima, PER.
David Fernando Narvaez-De Los RiosCardiology, Fundación Valle Del Lili, Cali, COL.
Daniel Ibanez VasquezInternal Medicine, Universidad Privada Del Valle, Cochabamba, BOL.
Sofia SimaluisaInternal Medicine, Faculty of Health Sciences "Eugenio Espejo," Universidad Tecnológica Equinoccial, Quito, ECU.
Anabel Huaman BozaInternal Medicine, Universidad Continental, Huancayo, PER.
Alison Cristina Jimenez OrdoñezGeneral Medicine, Universidad Latina, San Jose, CRI.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leprosy, or Hansen's disease, remains a public health concern, especially in endemic regions and among migrant populations. This case involves a patient from Venezuela living in Peru who initially presented with fever, weight loss, and respiratory symptoms without radiological findings. Physical examination revealed multiple erythematous nodules, hypopigmented macules, and thickened peripheral nerves. A skin smear confirmed multibacillary leprosy. The patient began standard multidrug therapy and showed gradual improvement. However, by the third month, he developed erythema nodosum leprosum (type 2 reaction), which was successfully treated with thalidomide without interrupting the main regimen. Follow-up showed complete resolution of skin lesions and neurological recovery. This case highlights an atypical presentation of multibacillary leprosy mimicking a respiratory infection. It emphasizes the importance of clinical suspicion in non-endemic areas with high migration rates. Early diagnosis and treatment are key to preventing permanent complications. Strengthening epidemiological surveillance and comprehensive care are essential for effective control of Hansen's disease.

Indexed as

clinical case reporterythema nodosum leprosumhansen diseaseleprosymigrant healthmultibacillary leprosymultidrug therapymycobacterium lepraeneglected tropical diseasestype 2 leprosy reaction

Identifiers

PMID41841056
PMCPMC12989240

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.