Evidence map›Paper›PMID 41841034›Full record

ArticleGastroenterology report2026

Liver graft as a 'Trojan horse': manifestation of variegate porphyria in an 11-month-old girl with biliary atresia after living-related liver transplantation.

Ulrich Stölzel, Birgit Knoppke, Thomas Stauch, Maria I von Eichborn, Herbert L Bonkovsky, Michael Melter

Abstract read
In one paragraph

Article in Gastroenterology report, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ulrich StölzelDivision of Internal Medicine II and Porphyria Center, Klinikum Chemnitz, D-09116 Chemnitz, Germany.
Birgit KnoppkeUniversity Children's Hospital Regensburg (KUNO), University Hospital Regensburg, D-93053 Regensburg, Germany.
Thomas StauchDeutsches Kompetenz-Zentrum für Porphyriediagnostik und Konsultation, MVZ Labor Volkmann und Kollegen GbR, D-76131 Karlsruhe, Germany.
Maria I von EichbornDepartment of Dermatology, University Hospital Regensburg, D-93053 Regensburg, Germany.
Herbert L BonkovskySection on Gastroenterology & Hepatology, Wake Forest University School of Medicine and Advocate Health Wake Forest Baptist Medicine, Winston-Salem, 27157 NC, United States.
Michael MelterUniversity Children's Hospital Regensburg (KUNO), University Hospital Regensburg, D-93053 Regensburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report on an infant girl with biliary atresia, who, at the age of 6 months, received a living-related liver transplantation (LRLT), (segments II/III) from her 37-year-old healthy mother. Five months after LRLT, the child developed skin lesions on sunlight exposed skin areas. Based on plasma fluorescence scanning, biochemical findings and DNA testing variegate porphyria (VP) was diagnosed in the girl. In this remarkable case hepatic heme synthesis was induced in the transplanted liver through medication (metamizole), stress and infection (cholangitis), unmasking previously undiscovered partial enzyme deficiency of PPOX. LRLT with subsequent manifestation of heterozygous VP in very early childhood has not been described hitherto. Our report will increase awareness of "rare risks" for "rare diseases" in liver transplantation.

Indexed as

biliary atresialight sensitivityliver transplantationphyriaporphyriavariegate por

Identifiers

PMID41841034
PMCPMC12989146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.