Evidence map›Paper›PMID 41840931›Full record

ArticleACS applied materials & interfaces2026

Development of a Cerium-Doped Titanate/Polyphenol Nanostructured Coating for Titanium Implants: Enhancing Antibacterial Properties through Ciprofloxacin Release.

Marcel Jakubowski, Mateusz Hegmit, Maria Ratajczak, Marta Trzaskowska, Aleksandra Maciejczyk, Agata Przekora, Monika Zielińska, Łukasz Ławniczak, Silvia Spriano, Mariusz Sandomierski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marcel JakubowskiInstitute of Chemical Technology and Engineering, Poznan University of Technology, ul. Berdychowo 4, 60-965 Poznań, Poland.ORCID 0009-0003-3009-2479
Mateusz HegmitInstitute of Chemical Technology and Engineering, Poznan University of Technology, ul. Berdychowo 4, 60-965 Poznań, Poland.
Maria RatajczakInstitute of Building Engineering, Poznan University of Technology, ul. Piotrowo 5, 60-965 Poznań, Poland.
Marta TrzaskowskaDepartment of Tissue Engineering and Regenerative Medicine, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.
Aleksandra MaciejczykDepartment of Tissue Engineering and Regenerative Medicine, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.
Agata PrzekoraDepartment of Tissue Engineering and Regenerative Medicine, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.ORCID 0000-0002-6076-1309
Monika ZielińskaInstitute of Chemical Technology and Engineering, Poznan University of Technology, ul. Berdychowo 4, 60-965 Poznań, Poland.ORCID 0000-0002-8850-6270
Łukasz ŁawniczakInstitute of Chemical Technology and Engineering, Poznan University of Technology, ul. Berdychowo 4, 60-965 Poznań, Poland.
Silvia SprianoDISAT Department, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy.ORCID 0000-0002-7367-9777
Mariusz SandomierskiInstitute of Chemical Technology and Engineering, Poznan University of Technology, ul. Berdychowo 4, 60-965 Poznań, Poland.ORCID 0000-0001-8227-8062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Titanium implants are widely used in orthopedics and dentistry; however, their long-term performance is challenged by bacterial colonization, lack of antioxidant activity, and mismatch in mechanical properties with bone tissue. In this study, we developed a hybrid nanostructured coating composed of cerium-doped titanate and a poly(tannic acid) layer, further functionalized with ciprofloxacin to enhance antibacterial properties. The coating was synthesized through sequential hydrothermal, ion-exchange, and polyphenol deposition steps, followed by antibiotic loading. Comprehensive characterization using SEM, AFM, XPS, FT-IR, and nanoindentation confirmed the successful formation of a uniform nanostructured coating with drug adsorption capability. Antioxidant activity studies demonstrated the material's ability to scavenge both free radicals and hydrogen peroxide. The obtained materials also exhibited the ability to neutralize intracellular reactive oxygen species (ROS). The scavenging of free radicals was facilitated by the polyphenolic component of the coating, whereas the decomposition of H

Indexed as

Anti-Bacterial AgentsCeriumCiprofloxacinCoated Materials, BiocompatibleNanostructuresPolyphenolsTitaniumAnimalsDrug LiberationHumansMicrobial Sensitivity TestsOsteoblastsProstheses and ImplantsPseudomonas aeruginosaStaphylococcus aureusAnti-Bacterial AgentsCeriumCiprofloxacinCoated Materials, BiocompatiblePolyphenolsTitaniumciprofloxacindrug deliverynanostructured coatingpolyphenolstitanium implants

Identifiers

PMID41840931
PMCPMC13298815

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.