Evidence map›Paper›PMID 41840881›Full record

ArticleJournal of agricultural and food chemistry2026

Serological Cross-Reactivity and Potential Allergenic Risk of Edible Cricket Proteins in Children and Adolescents with House Dust Mite Allergy.

Thanakrit Khammeethong, Pharima Phiriyangkul, Siriluk Khumsui, Pathitta Meeboongirt, Napa-Ai Suriyabhivadh, Chotika Yokthongwattana, Chama Inson, Yiwa Suksawat, Chomdao Sinthuvanich

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Article in Journal of agricultural and food chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thanakrit KhammeethongDepartment of Biochemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
Pharima PhiriyangkulDepartment of Science and Bioinnovation, Faculty of Liberal Arts and Science, Kamphaeng Saen Campus, Kasetsart University, Nakhon Pathom 73140, Thailand.
Siriluk KhumsuiDepartment of Biochemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
Pathitta MeeboongirtDepartment of Biochemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
Napa-Ai SuriyabhivadhBangkok Patana School, 643 La Salle Road (Sukhumvit 105), Bangna Tai, Bangna, Bangkok 10260, Thailand.
Chotika YokthongwattanaDepartment of Biochemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.
Chama InsonDepartment of Entomology, Faculty of Agriculture, Kasetsart University, Bangkok 10900, Thailand.
Yiwa SuksawatDivision of Allergy, Department of Pediatrics, Phramongkutklao Hospital, Bangkok 10400, Thailand.
Chomdao SinthuvanichDepartment of Biochemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.ORCID 0000-0002-2432-2122

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Edible insects are gaining popularity worldwide, particularly in their processed forms. However, edible insect consumption remains limited for some consumers due to reports of allergic reactions. Additionally, insect allergies have been documented in patients with a history of dust mite and crustacean allergies, suggesting potential cross-reactivity. This study aimed to evaluate the cross-reactivity of proteins from edible crickets in Thai patients aged 7-17 years with diagnosed dust mite allergies who had never previously consumed insects. Our findings indicate that thermal processing alters protein solubility, as evidenced by more pronounced IgG signals in the insoluble fractions than in the soluble fractions. Furthermore, immunoblot and liquid chromatography-mass spectrometry analyses identified tropomyosin and actin as potential cross-reactive allergens between edible crickets and house dust mites. These results suggest that individuals with dust mite allergies may be at an increased risk of allergic reactions after consuming edible crickets.

Indexed as

AllergensDust Mite AllergyFood HypersensitivityGryllidaeInsect ProteinsPyroglyphidaeAdolescentAnimalsChildCross ReactionsFemaleHumansImmunoglobulin GMaleTropomyosinAllergensImmunoglobulin GInsect ProteinsTropomyosinallergyhouse cricketshouse dust mitestropomyosintwo-spotted crickets

Identifiers

PMID41840881
PMCPMC13022853

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.